DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip1 and MPL1

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_568295.2	Gene:	MPL1 / 831268	AraportID:	AT5G14180	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	371	Identity:	110/371 - (29%)
Similarity:	179/371 - (48%)	Gaps:	54/371 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 YGYESEVHHVTTEDGYILTMHRI--RKQGA--------PPFLLQHGLVDSSAGFVVMGPNVSLAY 129
            :||:.|.|.|.|:|||||.|.||  .:.||        .|.|:|||::.....:::...:.:|..
plant    59 FGYKCEEHDVVTQDGYILNMQRIPEGRAGAVAGDGGKRQPVLIQHGILVDGMSWLLNPADQNLPL 123

  Fly   130 LLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFPKLHYA 194
            :|||..:|||:||.||.|:||.|..|:|.:..||:::|.|:..||||||.||:..:|| .|:||.
plant   124 ILADQGFDVWMGNTRGTRFSRRHKYLNPSQRAFWNWTWDELVSYDLPAMFDHIHGLTG-QKIHYL 187

  Fly   195 GHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSSIREMFNG 259
            |||.|....|...|.: ...|:|.|...|:|..|..             :..:::|....:.|..
plant   188 GHSLGTLIGFASFSEK-GLVDQVRSAAMLSPVAYLS-------------HMTTVIGDIAAKTFLA 238

  Fly   260 EFRFLCRMTEETER----------LCIEA-------VFGIVGRNWNEFNRKMFPVILGHYPAGVA 307
            |...:....|...:          :|::|       |..|.|:|.. .|.....:.|.:.|...:
plant   239 EATSILGWPEFNPKSGLVGDFIKAICLKAGIDCYDLVSVITGKNCC-LNASTIDLFLANEPQSTS 302

  Fly   308 AKQVKHFIQIIKSGRFAPYSY-SSNKNMQLYRDHLPPRYNLSLV--TVPTFVYYSTNDLLCHPKD 369
            .|.:.|..|.::......|:| ||::|::.|...:||.||:|.:  .:|.|..|...|.|...||
plant   303 TKNMIHLAQTVRDKELRKYNYGSSDRNIKHYGQAIPPAYNISAIPHELPLFFSYGGLDSLADVKD 367

  Fly   370 VESMCD-----DLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRM 410
            ||.:.|     |:..:..:::   |::.|.||:..:..:.::|.::
plant   368 VEFLLDQFKYHDIDKMNVQFV---KDYAHADFIMGVTAKDVVYNQV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	21/56 (38%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	93/320 (29%)
MPL1	NP_568295.2	PLN02872	16..415	CDD:215470	110/371 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070