Protein Alignment Lip1 and LIPK

DIOPT Version :9

• Sequence 1: NP_001285811.1
• Gene: Lip1 / 43973
• FlyBaseID: FBgn0023496
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: XP_011538375.1
• Gene: LIPK / 643414
• HGNCID: 23444
• Length: 419
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 123/386 - (31%)
• Similarity: 198/386 - (51%)
• Gaps: 54/386 - (13%)

  Fly    59 NIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRI--------RKQGAPPFLLQHGLVDSS 115
            |...::.:::.::|:.:||..|.:.|||:|||||.::||        |....|...|||||:.|:
Human    46 NANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASA 110

  Fly   116 AGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMID 180
            :.::...||.|||:||||..|||||||:|||.:||.|..|.|...::|.||..|:..|||||.|:
Human   111 SNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATIN 175

  Fly   181 HVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETED----------- 234
            .:::.||..:|:|.|||||.|..|:..|..|....|:....||||.|..|.|:.
Human   176 FIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR 240

  Fly   235 -----------HPYIRAISLYFNSLVGSSI--REMFNGEFRFLCRMTEETERLCIEAVFGIVGRN 286
                       ||:     ..|:..:.:.:  |::|              .|:|...:|.:.|.:
Human   241 VVKVLFGDKMFHPH-----TLFDQFIATKVCNRKLF--------------RRICSNFLFTLSGFD 286

  Fly   287 WNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSY-SSNKNMQLYRDHLPPRYNLSLV 350
            ....|.....|.|.|.|||.:.:.:.|:.|.:.||:...:.: :|::||..:....||.||::.:
Human   287 PQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKM 351

  Fly   351 TVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRML 411
            .|||.::....|::..|||||::...:.|:....|:|  .:||:||....|..:.:|:.::
Human   352 EVPTAIWNGGQDIVADPKDVENLLPQIANLIYYKLIP--HYNHVDFYLGEDAPQEIYQDLI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	22/58 (38%)
		Abhydrolase_1	103..399	CDD:278959	105/320 (33%)
LIPK	XP_011538375.1	PLN02872	31..410	CDD:215470	123/384 (32%)
		Abhydro_lipase	55..117	CDD:282003	22/61 (36%)
		Abhydrolase_5	99..>246	CDD:289465	61/146 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141848
Domainoid	1	1.000	222	1.000	Domainoid score	I2592
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	271	1.000	Inparanoid score	I3005
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.910