DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip1 and CG17097

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster

Alignment Length:	401	Identity:	152/401 - (37%)
Similarity:	217/401 - (54%)	Gaps:	18/401 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 EDEEDEEEEEEEEESVEDETPE-------DRLQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTED 88
            :|...|...:.::..:...|||       :.|.:::|..::.|:...||.||||.||.::||:||
  Fly   682 QDNLAESNIQTQKNRINVVTPEYKVFKTPNYLTQEDILDNTKLTTVDLIEKYGYPSETNYVTSED 746

  Fly    89 GYILTMHRIRKQGAPPFLLQHGLVDSSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHT 153
            ||.|.:|||.:.||.|.||.|||:.|||.:|.:||...|||:|....||||:.|.|||.|||.:.
  Fly   747 GYRLCLHRIPRPGAEPVLLVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENL 811

  Fly   154 TLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVV 218
            ......:|:||||:||||.:|:||.|||:|..|..||:.|.|||||.|.||||||.||.|..||.
  Fly   812 NRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVN 876

  Fly   219 SMQALAPAVYAKETEDHPYIRAI-------SLYFNSLVGSSI--REMFNGEFR-FLCRMTEETER 273
            .||||:|.||.:|... |.::.:       |:..|.|.|..|  :.....:|| .:|..:|....
  Fly   877 LMQALSPTVYLQENRS-PVLKFLGMFKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSGSELGSS 940

  Fly   274 LCIEAVFGIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYR 338
            :|....|.:.|.:|..||..:.|::..|...|.:|||:.|:.|:.....|..:.:.:..|...|.
  Fly   941 ICAIFDFVLCGFDWKSFNTTLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHGAVLNRVRYE 1005

  Fly   339 DHLPPRYNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVR 403
            ...||.||||..|....:::...|.|....||..:.:.|.|:.....|..:.|:|.||..:.|||
  Fly  1006 SSEPPAYNLSQTTSKVVLHHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVR 1070

  Fly   404 KMLYRRMLQVL 414
            .:||..:|:.|
  Fly  1071 PLLYSHVLRHL 1081

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	30/50 (60%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	117/305 (38%)
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	30/53 (57%)
		MhpC	746..1061	CDD:223669	123/315 (39%)
		Abhydrolase_5	762..>899	CDD:289465	73/137 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438257
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850