DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip1 and Lipo1

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_006231364.1	Gene:	Lipo1 / 294097	RGDID:	1565682	Length:	397	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	119/385 - (30%)
Similarity:	196/385 - (50%)	Gaps:	35/385 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRI------RKQGAPPFLL--QHGL 111
            |...|...:|.::|.::|..:.|.|..:.|.|:|||||.::||      ....||..::  ||||
  Rat    20 LLEPNKNPESHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGL 84

  Fly   112 VDSSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLP 176
            ..:...:|...|:.|||::||:..|||||||:||:.:::.|.||.||..:||.||:.::..||||
  Rat    85 FSTPGVWVANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLP 149

  Fly   177 AMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAI 241
            |.|:.:|..||..:::|.|||.|........|......:|:.....:||....|      |::.
  Rat   150 ATINFILNTTGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVK------YVKG- 207

  Fly   242 SLYFNSLVGSSIREMFN---GEFRFLCRM--TEETERLC----IEA----VFG-IVGRNWNEFNR 292
               |..|:.....|.|.   |:..||..:  :|.::.:|    ::|    |.| :.|.:.::.|.
  Rat   208 ---FGRLLAYFSPEAFKLVFGKKEFLPTVVFSEYSKYVCNIKLVDAGCAGVLGSLTGFSEDQLNT 269

  Fly   293 KMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSS-NKNMQLYRDHLPPRYNLSLVTVPTFV 356
            ....|.:.|..||.:.:.:.|..|.|:||.|..|.:.| :.|||.|....||.|::..:.|||.:
  Rat   270 SRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENMKVPTVM 334

  Fly   357 YYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGK 416
            :....|.|..||||.::...:.|:.....:|  ||:|:||:..::.:..:...:|.:||:
  Rat   335 FTGLKDFLADPKDVANLVPKIFNLIYHKTIP--EFSHLDFIVGLNAKTEVSDEILTILGE 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	19/58 (33%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	99/312 (32%)
Lipo1	XP_006231364.1	Abhydro_lipase	33..94	CDD:282003	20/60 (33%)
		Abhydrolase_1	77..375	CDD:278959	98/309 (32%)
		Abhydrolase_5	77..>199	CDD:289465	46/121 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.910