DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip1 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	375	Identity:	119/375 - (31%)
Similarity:	175/375 - (46%)	Gaps:	50/375 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 SVDKLIAKYGYESEVHHVTTEDGYILTMHRIR--KQG---APPFLLQHGLVDSSAGFVVMGPNV- 125
            ::.::...:||..|.|.|.|:|.:||.:|||.  ||.   .......|||:.:|..:|.:..:.
pombe    74 NIYEICEAFGYRVEEHLVRTQDNFILCLHRITHPKQSQHKREVVYCHHGLMTNSELWVAVNESER 138

  Fly   126 SLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFPK 190
            ||.::|.:..|||||||.|||:|||.|.|..|.:.:||:||..::.|:|:|..:|::|:.||..|
pombe   139 SLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREK 203

  Fly   191 LHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSSIRE 255
            |:|.|.|||........|:.|..||||.....|||| ||.        :..|.||...:.....:
pombe   204 LNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPA-YAP--------KGFSNYFVDYIVKVNPK 259

  Fly   256 MFNGEFRFLCRMTEET--ERLCIEAVF-GIVG------RNWNEFNRKMFPVILG--HYPAGVAAK 309
            :....|...|.:...|  :.:|...:| .||.      .||:..|..:...:.|  |..:..:.|
pombe   260 IMYHLFGRRCLLPSVTFWQNICYPPIFVKIVDVSLKILFNWDLSNISLNQKLCGYAHLYSFSSVK 324

  Fly   310 QVKHFIQIIKSGRFAPYSYSSNKNMQLYRDH--LPPRYNLSLVTVPTFVYYSTNDLLCHPKDVES 372
            .|.|::||||           |...|||.|.  |...|......||.|   .||::.|....:..
pombe   325 SVVHWLQIIK-----------NCTFQLYDDDMALLAGYGSRHYQVPLF---PTNNIKCPMLILWG 375

  Fly   373 MCDDLGN--VTGKYLVPQ-KE-----FNHMDFLWAIDVRKMLYRRMLQVL 414
            ..|.|.|  |....|.|. ||     :.|:||||..||::.::..::..|
pombe   376 GKDTLINMEVMRTALPPHAKEVSIAHYEHLDFLWGQDVKEEVFPVVIDAL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	19/55 (35%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	101/317 (32%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	18/55 (33%)
		Abhydrolase_1	116..410	CDD:278959	101/316 (32%)
		Abhydrolase	<171..>242	CDD:304388	29/71 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870