DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip1 and SPCC1672.09

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_587880.1	Gene:	SPCC1672.09 / 2539344	PomBaseID:	SPCC1672.09	Length:	467	Species:	Schizosaccharomyces pombe

Alignment Length:	410	Identity:	124/410 - (30%)
Similarity:	186/410 - (45%)	Gaps:	45/410 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRKQG-----------APPFLLQ 108
            |||.....|:. .:.::....||..|.|.|.|||.|||.:|||.|..           .|.....
pombe    69 LQRAKAIHDAA-DIREMCKISGYYVEDHLVRTEDDYILCIHRISKDSPGRIGSPHPKKLPVVYCH 132

  Fly   109 HGLVDSSAGFVV-MGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGM 172
            |||:.:|..:|. :.|...|.:.|.:..|||||||.|||:|||.|...|..:.:|||||..:...
pombe   133 HGLLMNSEVWVCNVDPRNCLVFDLVNKGYDVWLGNNRGNKYSRQHLRFDSTDKEFWDFSIDDFAQ 197

  Fly   173 YDLPAMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDH-- 235
            ||:|..||::||.:|..||.|.|.|||....|...|:.|..|||:.|:.|||||:..|...:.
pombe   198 YDIPDTIDYILKTSGQTKLTYIGFSQGTAQAFASLSIHPLLNDKINSLIALAPAISPKGLHNRVV 262

  Fly   236 -PYIRA-ISLYFNSLVGSSIREMFNGEFRFLC-RMTEETERLCIEAVFGIVGRNWNEFNRKMFP- 296
             .:::| .|:.|......||.........||. :..:.....|:..:|     ||:..|...:.
pombe   263 DAFVKARPSILFFLFGRKSILPSAGFWQSFLAPKFFDAVLAYCLSQLF-----NWSCQNISSYQR 322

  Fly   297 -VILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYRDHLPPRYNLSL-----VTVPTF 355
             |...|..:..:.|.:.|:.||::|..|..|.     |.||..|:....|..:.     :..|.:
pombe   323 LVSFAHLYSYTSVKCLVHWFQIMRSAEFRMYD-----NDQLGHDYFLKYYKAAKFPTNNIRTPIY 382

  Fly   356 VYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGKV--- 417
            :.:..:|.|.   |:::|.:.|......  |....:.|:|.:||..|:..:...:|:.|..:
pombe   383 LIWGGSDSLV---DIQAMLNALPAEVEH--VKVDSYEHLDMIWADTVKDYVIPPVLRRLRDIHHP 442

  Fly   418 PEGSPEEANRSRREIRGKFI 437
            ||  .||.::..|||:...|
pombe   443 PE--HEENDKENREIQKNHI 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	21/62 (34%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	92/308 (30%)
SPCC1672.09	NP_587880.1	Abhydro_lipase	81..145	CDD:282003	21/63 (33%)
SPCC1672.09	NP_587880.1	Abhydrolase_1	127..422	CDD:278959	93/309 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870