DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip1 and AgaP_AGAP002353

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_312606.4	Gene:	AgaP_AGAP002353 / 1273610	VectorBaseID:	AGAP002353	Length:	415	Species:	Anopheles gambiae

Alignment Length:	368	Identity:	157/368 - (42%)
Similarity:	222/368 - (60%)	Gaps:	20/368 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 QDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRK---QGAPPFLLQHGLVDSSAGFVVMGP 123
            :|..|||.:|::||||..|.|.::|:|||.||:||::.   ......||.|||:.|||.::::||
Mosquito    42 EDGRLSVPELVSKYGYHVEEHSLSTDDGYRLTIHRVQAASYTNGTVVLLMHGLLCSSADWLMIGP 106

  Fly   124 NVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDP-DESKFWDFSWHEIGMYDLPAMIDHVLKVTG 187
            ..:||||||:..|||||||||||||||:|.:::| |::.||.|||||||.||:||.||::|:.||
Mosquito   107 GNALAYLLANEGYDVWLGNARGNRYSRDHASINPDDDNSFWKFSWHEIGRYDIPATIDYILEQTG 171

  Fly   188 FPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSS 252
            ..:|.|.|||||.|.||||.|.||.||||::.|.||||..:....:. |.:|.::.:..:|  ..
Mosquito   172 HRRLQYVGHSQGTTGFFVMASTRPEYNDKIIQMNALAPVAFMGHMKS-PLLRFMTKFLKTL--DI 233

  Fly   253 IREMFN-GEF-----------RFLCRMTEETE-RLCIEAVFGIVGRNWNEFNRKMFPVILGHYPA 304
            :..:|. |||           :.:|....... .:|...:|.:.|.|.::.:..|.|::.||.||
Mosquito   234 LLAVFGVGEFMPNKPILHEIAQLICPPNSTVHINMCAHLLFLLAGYNPSQLDPVMLPILFGHTPA 298

  Fly   305 GVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYRDHLPPRYNLSLVTVPTFVYYSTNDLLCHPKD 369
            |.|.:|:.|:.|.:.|.||..|.|...||:.:|....||.|:||.||.|..:||..||.|..|:|
Mosquito   299 GSATRQLVHYAQEVLSNRFEMYDYGKLKNVLIYGSATPPEYDLSRVTAPVVMYYGLNDFLATPED 363

  Fly   370 VESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQ 412
            |..:...|.|:.....|....|||:|||.|.|||.:||..:::
Mosquito   364 VNRLARKLPNLKRSVAVNDVLFNHLDFLIASDVRHLLYEPVME 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	23/53 (43%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	132/309 (43%)
AgaP_AGAP002353	XP_312606.4	Abhydro_lipase	48..105	CDD:282003	24/56 (43%)
		PLN02872	50..402	CDD:215470	152/354 (43%)
		Abhydrolase_5	<291..387	CDD:289465	37/95 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
TreeFam	1	0.960	-	-
	7	6.790