DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip1 and AgaP_AGAP013368

DIOPT Version :9

Sequence 1:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_003436388.1	Gene:	AgaP_AGAP013368 / 11175553	VectorBaseID:	AGAP013368	Length:	437	Species:	Anopheles gambiae

Alignment Length:	403	Identity:	152/403 - (37%)
Similarity:	222/403 - (55%)	Gaps:	37/403 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 RLQRKNIKQDSTLSV---------DKLIAKYGYESEVHHVTTEDGYILTMHRI----RKQGAP-- 103
            :||.....:|..:.:         .:|:.|||||.|:|.|.|||||:|.::||    ...|.|
Mosquito    32 QLQSSRTSRDRAIRMLGVVNETRRPQLVWKYGYEIEIHEVQTEDGYLLDLYRIAGRRAASGQPPL 96

  Fly   104 ------PFLLQHGLVDSSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPD--ES 160
                  |..|.|.|:.|.|.:|:|||..:|||||||..:|||:|||||.||||.|...|||  ..
Mosquito    97 RPHRNAPIFLMHSLLSSCADWVLMGPGRALAYLLADAGFDVWMGNARGTRYSRKHLHHDPDARAG 161

  Fly   161 KFWDFSWHEIGMYDLPAMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAP 225
            :||:|||||||:||:.|:|||||..||..:|||.|.|||....||:.|.||.|:.|::.|||::|
Mosquito   162 EFWNFSWHEIGLYDVRALIDHVLNATGAARLHYGGFSQGTMVLFVLLSERPEYSAKLIDMQAISP 226

  Fly   226 AVYAKETEDHPYIRAISLYFNSLV----GSSIREMF-NGEF-----RFLCRMTEETERLCIEAVF 280
            :||....|.. .:|......:.||    .:..||:. |..|     :.:|  .:....:|.|.::
Mosquito   227 SVYMYRLEGR-IVRTFVTLADPLVAALDAAGRREILPNRRFIAPLVKIVC--ADGNVTVCRELLY 288

  Fly   281 GIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYRDHLP-PR 344
            .:.|||..:.:.:|..:.|||:|||.:.:|:.||.|||::.|||.||...:.....:....| |.
Mosquito   289 DVAGRNPAQVDDRMLRIFLGHFPAGASLRQLHHFSQIIRTARFAKYSPLRSTGRGGFHASPPAPL 353

  Fly   345 YNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRR 409
            |||:..|||..|||..||.:.:.:|...:.|::.|:...:.:..:.|.|.||:.|.:..::|...
Mosquito   354 YNLTRATVPVVVYYGLNDHVINYRDALQLADEVPNLAAVHQIADRHFTHSDFILAKNSARLLNSI 418

  Fly   410 MLQVLGKVPEGSP 422
            :||.|.:....:|
Mosquito   419 LLQELDQYDRRAP 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	26/62 (42%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	125/316 (40%)
AgaP_AGAP013368	XP_003436388.1	Abhydro_lipase	56..121	CDD:282003	26/64 (41%)
AgaP_AGAP013368	XP_003436388.1	Abhydrolase_1	103..404	CDD:278959	122/303 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
TreeFam	1	0.960	-	-
	8	7.890