DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lip1 and Lipo2

DIOPT Version :9

Sequence 1:NP_001285811.1 Gene:Lip1 / 43973 FlyBaseID:FBgn0023496 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001309267.1 Gene:Lipo2 / 101055671 MGIID:3644466 Length:398 Species:Mus musculus


Alignment Length:384 Identity:122/384 - (31%)
Similarity:205/384 - (53%) Gaps:39/384 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 RKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRI------RKQGAPPFLL--QHGLVD 113
            :||  .::.::|.::|..:.|.||.:.|.|:|||||.::||      .|..||..::  ||||:.
Mouse    24 KKN--PEAHMNVSEIIKHWDYPSEEYEVVTDDGYILPINRIPHGKNNAKSPAPKMVVFCQHGLLA 86

  Fly   114 SSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAM 178
            :...:|...|..|||::|||..||||:|::||:.:::.|.||:||..:|||||:.::..|||||.
Mouse    87 TPGAWVSNPPVNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNPDSKEFWDFSFDQMIKYDLPAT 151

  Fly   179 IDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKV---VSMQALAPAVYAKETEDHPYIRA 240
            |:.:|..||..:::|.|||||.    ::.....|.|.|:   :.:..|...:|:.:     :.:.
Mouse   152 INFILDKTGQKQIYYIGHSQGT----LLAIGAFATNQKLAEKIKLNILLAPIYSVQ-----HSKG 207

  Fly   241 ISLYFNSLVGSSIREMFNGEFRFL------------CRMTEETERLCIEAVFGIVGRNWNEFNRK 293
            ||...:.|..::|:.:| ||..||            |.:...| .:|...:..:.|.:..|.|:.
Mouse   208 ISHLASYLTPTTIKLLF-GEKEFLPTVVFSEVGACVCNINFFT-AICAAIMGSMGGYSPEELNKS 270

  Fly   294 MFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSS-NKNMQLYRDHLPPRYNLSLVTVPTFVY 357
            ...|.:....||.:.|.:.|:.|:.:||....|.:.| :.||:.|....||.||:..:.|||.::
Mouse   271 RLDVYVKLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLNMRHYNQTTPPVYNVEDMKVPTAMF 335

  Fly   358 YSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGK 416
            ....|.|..|:|||.:...:.|:|  ||....:|:|.||:|.::.|:.:...:|.:|.|
Mouse   336 TGLKDFLSDPEDVEILKPKIHNLT--YLKTIPDFSHFDFIWGLNTREEVSEEILTILRK 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lip1NP_001285811.1 Abhydro_lipase 71..122 CDD:282003 21/58 (36%)
Abhydrolase_1 103..399 CDD:278959 99/313 (32%)
Lipo2NP_001309267.1 PLN02872 34..391 CDD:215470 117/369 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831883
Domainoid 1 1.000 227 1.000 Domainoid score I2491
eggNOG 1 0.900 - - E2759_KOG2624
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 278 1.000 Inparanoid score I2905
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG55134
OrthoDB 1 1.010 - - D408561at33208
OrthoFinder 1 1.000 - - FOG0000083
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11005
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X80
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1211.910

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