DRSC/TRiP Functional Genomics Resources

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Protein Alignment spag and Hop1

DIOPT Version :10

Sequence 1:NP_524664.1 Gene:spag / 43958 FlyBaseID:FBgn0015544 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_172691.1 Gene:Hop1 / 837781 AraportID:AT1G12270 Length:572 Species:Arabidopsis thaliana


Alignment Length:451 Identity:87/451 - (19%)
Similarity:151/451 - (33%) Gaps:121/451 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 EQDIKNKEKELQKSPLS---------------------------------AANKDLPVRSHVQTD 63
            :.|..|..:|:||:|.|                                 ....|:...|..:.:
plant   152 QPDFVNMMQEIQKNPSSLNLYLKDQRVMQSLGVLLNVKFRPPPPQGDEAEVPESDMGQSSSNEPE 216

  Fly    64 KSRKESPSSSAASSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAVYPH 128
            ..:|..|........||:::     ..::.:||...|:.||...|:.::|.||..|||||.:...
plant   217 VEKKREPEPEPEPEVTEEKE-----KKERKEKAKKEKELGNAAYKKKDFETAIQHYSTAIEIDDE 276

  Fly   129 DPIYHINRALCYLKQESFDQCVEDCEAAIALD-------KLCVKAYYRRMQANESLGNNMEALKD 186
            |..|..|||..||:...:::|:|||..|:...       |:..:|..|:   ..:|....:..||
plant   277 DISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARALTRK---GTALTKMAKCSKD 338

  Fly   187 CTTVLAIEPKNIEAKR---SLARINDRLRKIATKSGPNFTPDRPGMIEILPIEKPAYKRSKKAMR 248
            ....:....|.:...|   :|.|:||.                              :|:||...
plant   339 YEPAIEAFQKALTEHRNPDTLKRLNDA------------------------------ERAKKEWE 373

  Fly   249 SVPVVDVVSPRATIDDSNQLRISDEDIDK--IFNSNCGIIEEVK------KTNP--------KPT 297
            .....|.             ::.||:.:|  .|.......|.:|      |.||        :..
plant   374 QKQYFDP-------------KLGDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAA 425

  Fly   298 PMPDTSGPPKAETIAKTSKEVKPTKQTAVKVAPAVE-TPKETETRKDT---KIVPESDNEAKPSA 358
            ........|:....|:...|:.||.........||: ..||.:...:|   .:..:..|:.....
plant   426 SYTKLGAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQELLDG 490

  Fly   359 PKKTAVEVPKVQTQVSPPKTTIER------SPEVNTVQTEKI-EQASSNNAMSPSPIERFL 412
            .|:...::.|.......|:...||      .||:..:.|:.: .|..|:...:||..::.:
plant   491 VKRCVQQINKANRGDLTPEELKERQAKGMQDPEIQNILTDPVMRQVLSDLQENPSAAQKHM 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spagNP_524664.1 TPR repeat 96..124 CDD:276809 12/27 (44%)
TPR 102..>211 CDD:440225 35/118 (30%)
TPR repeat 129..159 CDD:276809 12/29 (41%)
TPR repeat 164..192 CDD:276809 5/27 (19%)
PLN03209 <296..416 CDD:178748 23/128 (18%)
RPAP3_C 416..503 CDD:464012
Hop1NP_172691.1 PLN03088 1..>101 CDD:215568
TPR repeat 2..30 CDD:276809
TPR repeat 35..65 CDD:276809
TPR repeat 70..98 CDD:276809
STI1 133..187 CDD:436075 7/34 (21%)
TPR 250..277 CDD:197478 11/26 (42%)
TPR 271..549 CDD:440225 61/323 (19%)
TPR repeat 277..307 CDD:276809 12/29 (41%)
TPR repeat 319..350 CDD:276809 6/33 (18%)
TPR repeat 387..411 CDD:276809 4/23 (17%)
TPR repeat 416..446 CDD:276809 2/29 (7%)
TPR repeat 451..479 CDD:276809 5/27 (19%)
Blue background indicates that the domain is not in the aligned region.

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