Protein Alignment spag and spag1b

DIOPT Version :10

• Sequence 1: NP_524664.1
• Gene: spag / 43958
• FlyBaseID: FBgn0015544
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001428503.1
• Gene: spag1b / 768178
• ZFINID: ZDB-GENE-061013-512
• Length: 607
• Species: Danio rerio
• Alignment Length: 482
• Identity: 105/482 - (21%)
• Similarity: 182/482 - (37%)
• Gaps: 104/482 - (21%)

  Fly    20 EYENSVKDLYSWEQDIKNKEKELQKSPLSAANKDL-PVRSH---VQTDKSRKESPSSSAASSP-T 79
            |:.:..:||..||:.::..|..|.:|.:.::.:.: ||||.   :||::.:|::..:|....| |
Zfish    83 EWRSITEDLQVWERSVRMTEAALMRSSIFSSEECVPPVRSSHRVLQTNQEKKKTVKTSCTPRPYT 147

  Fly    80 EKQDLPVD------------------PVAQQ-------------YKKANDIKDRGNTYVKQGEYE 113
            :.....||                  |..||             ...|...||:||...:..:||
Zfish   148 DWDRFDVDSACAGESVRNAPAAAAVCPEVQQRLSSCTALTAQEKQTAALREKDKGNEAYRSRDYE 212

  Fly   114 KAIVAYSTAIAVYPHDPIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLG 178
            :|:..|..::::.....::: |||...::.:.:...:.||:|.:.|:...:||..||...::.||
Zfish   213 EALDYYCRSLSLASSAAVFN-NRAQTLIRLQQWPAALSDCDAVLQLEPHNIKALLRRATVHKHLG 276

  Fly   179 NNMEALKDCTTVLAIEPKNIEAKRSLARINDRLRKIATKSGPNFTPDRPG----MIEILPIEKPA 239
            :..|:..|...||.|:|:|..|.:.||.:        :.:.|.....|.|    :.|:...|:.|
Zfish   277 HQQESHDDLRAVLQIQPQNKTALKLLADV--------SSTDPPQQTRRTGRRILIQEVEEEEEGA 333

  Fly   240 YKRSKKAMRSV------------------PVVDVVSPRATIDDSNQLRISDEDIDKIFNSNCGII 286
            :.......|.:                  ...|..|.....:|:......|||...      |.|
Zfish   334 HSEHSGESRGIMGNTHSSSSAGGAAHGDAHTEDTPSGHTHTEDTPLGHTHDEDTPP------GHI 392

  Fly   287 EEVKKTNPKPTPMPDTSG------PPKAETIAKTSKEVKPTKQTAVKVAPAVETPKETETRKDTK 345
             :.:.|....|.:.|||.      ||     .....|..|...|...|.|...|....|..|:|.
Zfish   393 -QTEDTPQGHTHIEDTSSGQMEVTPP-----GHIHNEATPPGHTPTNVTPPGHTHMMDEEHKETA 451

  Fly   346 IVPESDNEAKPSAPKKTAVEVPKVQTQVSPPKTTIERSPEVNTVQTEKIE----QASSNNAMSPS 406
            .....||    |....:.:|:.:...:|.......|.:.|..| |:.:::    .|.:|.|:...
Zfish   452 EQHTQDN----SEHTASELELLRHDGKVLFCSGCYEEAAEKYT-QSLQLDTHTCAAYTNRALCYI 511

  Fly   407 PIERF----------LPPAPTSTAQFH 423
            .:|||          |...||:...|:
Zfish   512 KLERFTEAQQDCDSALQIEPTNKKAFY 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spag	NP_524664.1	TPR repeat	96..124	CDD:276809	9/27 (33%)
		TPR	102..>211	CDD:440225	29/108 (27%)
		TPR repeat	129..159	CDD:276809	6/29 (21%)
		TPR repeat	164..192	CDD:276809	9/27 (33%)
		PLN03209	<296..416	CDD:178748	31/139 (22%)
		RPAP3_C	416..503	CDD:464012	3/8 (38%)
spag1b	NP_001428503.1	None