DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spag and CG34274

DIOPT Version :9

Sequence 1:	NP_524664.1	Gene:	spag / 43958	FlyBaseID:	FBgn0015544	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster

Alignment Length:	186	Identity:	44/186 - (23%)
Similarity:	83/186 - (44%)	Gaps:	26/186 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 REYENSVKDLYSWEQDIKN-----KEKELQKSPLSAANKDLPV--RSHVQT-----DKSRKESPS 71
            :|....|:|:..:...::|     ..|:.|||.::..:....|  ||.|.|     .|:::...:
  Fly    41 KEQPTKVEDVIEYLDVLENANKTDSSKKRQKSTITMDDIKCIVTRRSAVSTTTFRRGKAKRALIN 105

  Fly    72 SSAASSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYE-------KAIVAYSTAIAVYPHD 129
            ::..:...:....|.|.|..:.::    :|...|:.:.|.||       .|...||..|......
  Fly   106 TNQFTFMRQIDSEPDDRVLAREQR----EDVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDS 166

  Fly   130 PIYHINRALCYLKQESFDQCVEDCEAAIA-LDKLCVKAYYRRMQANESLGN--NME 182
            |:.::|||||::|...|...:.||:..:| :|:..::|:..|..|.:.|.:  |.|
  Fly   167 PVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLNDEPNFE 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spag	NP_524664.1	TPR_11	95..161	CDD:290150	20/73 (27%)
		TPR repeat	96..124	CDD:276809	8/34 (24%)
		TPR_1	102..129	CDD:278916	8/33 (24%)
		TPR repeat	129..159	CDD:276809	11/30 (37%)
		TPR	130..160	CDD:197478	11/30 (37%)
		TPR_16	136..197	CDD:290168	16/50 (32%)
		TPR repeat	164..192	CDD:276809	6/21 (29%)
		RPAP3_C	415..503	CDD:290588
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	18/61 (30%)
		TPR repeat	133..161	CDD:276809	7/27 (26%)
		TPR repeat	166..197	CDD:276809	11/30 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910