DRSC/TRiP Functional Genomics Resources

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Protein Alignment spag and ttc12

DIOPT Version :10

Sequence 1:NP_524664.1 Gene:spag / 43958 FlyBaseID:FBgn0015544 Length:534 Species:Drosophila melanogaster
Sequence 2:XP_009289931.1 Gene:ttc12 / 563791 ZFINID:ZDB-GENE-071016-4 Length:707 Species:Danio rerio


Alignment Length:321 Identity:64/321 - (19%)
Similarity:120/321 - (37%) Gaps:90/321 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SAQEKAFELQRQVRQNAREYE-------NSVKDLYSWEQDIKNKEKELQKSP---LSAANKDLPV 56
            |.||.|.....|:..:..:.|       .:|.:..|.|.:..|...|..::|   |....||  .
Zfish    37 SCQENAIVKTEQLISSLEQKEQFKTKINKTVINTSSSENNPLNIRYESSQNPENFLKILEKD--A 99

  Fly    57 RSHVQTDKSRKESPSSSAASSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYST 121
            ....|..|.::|                          :||.::::||....||:||.|:..|:.
Zfish   100 EDRCQRRKMKEE--------------------------RANVLREQGNEAFTQGDYETAVRFYTE 138

  Fly   122 AIAVYPHDPIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKD 186
            .:.........:.|||..::|.:.:.:.:.|||.|:..::.|:||:..       :|.:..||||
Zfish   139 GLEQLRDMQALYTNRAQAFIKLKRYKEAISDCEWALRCNEKCIKAFIH-------MGTSHLALKD 196

  Fly   187 CT-------TVLAIEPKNIEAKRSLARINDRLRKIATKSGPNFTPDRPGMIEILPIEKPAYKRSK 244
            .|       .:|.|||:.....::..|..|...|:..:                  ||.|::..:
Zfish   197 FTQSRICYRKILEIEPQRETMVKAYLRRVDMEEKVTLQ------------------EKAAWEELQ 243

  Fly   245 KAM-RSVPVVDVVSPRATIDDSNQLRISDEDIDKIFNSNCGIIEEVKKTNPKPTPMPDTSG 304
            :.. ::..:.|::.   .::..|::.:          ..||.:|.:.|.      :.|.||
Zfish   244 EGTGQATNIADLLK---KLERPNEINL----------YYCGGLELLSKA------IKDCSG 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spagNP_524664.1 TPR repeat 96..124 CDD:276809 10/27 (37%)
TPR 102..>211 CDD:440225 31/115 (27%)
TPR repeat 129..159 CDD:276809 8/29 (28%)
TPR repeat 164..192 CDD:276809 8/34 (24%)
PLN03209 <296..416 CDD:178748 3/9 (33%)
RPAP3_C 416..503 CDD:464012
ttc12XP_009289931.1 TPR 107..>269 CDD:440225 41/225 (18%)
TPR repeat 113..141 CDD:276809 10/27 (37%)
TPR repeat 146..176 CDD:276809 8/29 (28%)
TPR repeat 181..209 CDD:276809 8/34 (24%)
CoV_Spike_S1-S2_S2 <298..>411 CDD:424070
Blue background indicates that the domain is not in the aligned region.

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