Protein Alignment spag and ttc1

DIOPT Version :10

• Sequence 1: NP_524664.1
• Gene: spag / 43958
• FlyBaseID: FBgn0015544
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_068071942.1
• Gene: ttc1 / 492510
• ZFINID: ZDB-GENE-041114-80
• Length: 355
• Species: Danio rerio
• Alignment Length: 221
• Identity: 55/221 - (24%)
• Similarity: 94/221 - (42%)
• Gaps: 33/221 - (14%)

  Fly    26 KDLYSWEQDIKNKEKELQKSPLSAANK--DLPVRSHVQTDKSRKESPSSSAASSPTE-------- 80
            ||..|..:.::|.:..|..|..|..|:  .|....|:..|...::....:...|..|
Zfish    87 KDFGSETERLENTKPCLDHSDRSDENRRDSLTSDPHLDKDNDEEQEKWENDEHSDAEFKEETVKV 151

  Fly    81 -----------KQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAVYP-----HD 129
                       ::||..:....:.|::.::|::||...|.||:.:|..:||.|:.:.|     ..
Zfish   152 AEYDDEYLRELEKDLTEEDRESRRKESLELKEKGNAQFKSGEHVEAEESYSAALKLCPVCFTKDR 216

  Fly   130 PIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIE 194
            .|...|||...|.|:..|..:.||..||.|:...|:|..||.:..|......|||:|..|||..:
Zfish   217 SILFSNRAASRLHQDKKDGAISDCSKAIELNPNYVRAILRRAELYEKTDKLDEALEDYKTVLEKD 281

  Fly   195 PKNIEAKRSLARI-------NDRLRK 213
            |....|:.:..|:       |:::::
Zfish   282 PGIPAAREACMRLPRQIEERNEKMKE 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spag	NP_524664.1	TPR repeat	96..124	CDD:276809	10/27 (37%)
		TPR	102..>211	CDD:440225	38/120 (32%)
		TPR repeat	129..159	CDD:276809	11/29 (38%)
		TPR repeat	164..192	CDD:276809	11/27 (41%)
		PLN03209	<296..416	CDD:178748
		RPAP3_C	416..503	CDD:464012
ttc1	XP_068071942.1	NlpI	<152..>287	CDD:443815	39/134 (29%)
		TPR repeat	181..206	CDD:276809	10/24 (42%)
		TPR repeat	216..246	CDD:276809	11/29 (38%)
		TPR repeat	251..279	CDD:276809	11/27 (41%)