DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spag and Sgt

DIOPT Version :9

Sequence 1:	NP_524664.1	Gene:	spag / 43958	FlyBaseID:	FBgn0015544	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001246058.1	Gene:	Sgt / 35052	FlyBaseID:	FBgn0032640	Length:	331	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	63/284 - (22%)
Similarity:	113/284 - (39%)	Gaps:	67/284 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SSSAASSPTEK--------------------------QDLPVDPVAQQYKKANDIKDRGNTYVKQ 109
            |||.||:|.:.                          |.|..:...:....|..||:.||..:|:
  Fly    65 SSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKE 129

  Fly   110 GEYEKAIVAYSTAIAVYPHDPIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQAN 174
            .:|.:|::.|:.|||..|.:||::.|||..:::....::.|.||::|:..:....|||.|...|.
  Fly   130 NKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAY 194

  Fly   175 ESLGNNMEALKDCTTVLAIEPKNIEAKRSLARINDRLRKIATKSGPNFTPD----RPGMIEIL-- 233
            .::||..:|.:.....:.:||.|...|.:|.         |.::..|..|.    |..:|.:|
  Fly   195 SNMGNFEKAEQAYAKAIELEPDNEVYKSNLE---------AARNARNQPPQTGRLREDLINMLSQ 250

  Fly   234 PIEKPAYKRSK------KAMRSVPVVDVVSPRATIDDSNQLRISDEDIDKIF----------NSN 282
            |:.:..:..::      .:|...|:: :.:.|......|...:.::.:..|:          |||
  Fly   251 PMVRNLFNNAEIDVEQLLSMLQNPMI-MNTIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPNSN 314

  Fly   283 CGIIEEVKKTNPKPTPMPDTSGPP 306
                     .||.....|....||
  Fly   315 ---------ANPGNEQQPGNQPPP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spag	NP_524664.1	TPR_11	95..161	CDD:290150	22/65 (34%)
		TPR repeat	96..124	CDD:276809	10/27 (37%)
		TPR_1	102..129	CDD:278916	10/26 (38%)
		TPR repeat	129..159	CDD:276809	9/29 (31%)
		TPR	130..160	CDD:197478	9/29 (31%)
		TPR_16	136..197	CDD:290168	16/60 (27%)
		TPR repeat	164..192	CDD:276809	8/27 (30%)
		RPAP3_C	415..503	CDD:290588
Sgt	NP_001246058.1	SGTA_dimer	9..>48	CDD:293154
		TPR_11	116..177	CDD:290150	21/60 (35%)
		TPR_2	116..149	CDD:285020	13/32 (41%)
		TPR repeat	116..144	CDD:276809	10/27 (37%)
		TPR_17	139..170	CDD:290167	10/30 (33%)
		TPR repeat	149..179	CDD:276809	9/29 (31%)
		TPR_16	156..218	CDD:290168	16/61 (26%)
		TPR_1	184..217	CDD:278916	10/32 (31%)
		TPR repeat	184..212	CDD:276809	8/27 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840