DRSC/TRiP Functional Genomics Resources

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Protein Alignment spag and HIP-R

DIOPT Version :9

Sequence 1:NP_524664.1 Gene:spag / 43958 FlyBaseID:FBgn0015544 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_001014719.2 Gene:HIP-R / 31335 FlyBaseID:FBgn0029676 Length:377 Species:Drosophila melanogaster


Alignment Length:354 Identity:69/354 - (19%)
Similarity:125/354 - (35%) Gaps:75/354 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 NAREYENSVKDLYSWEQDIKNKEKELQKSPLSAANKDLPVRSHVQTDKSRKESPSSSAASSPTEK 81
            ||.|.....|.|...|.|:                 :|.:...::.| |....|..:.:...|| 
  Fly    75 NAPEDSEDEKSLSDPESDV-----------------ELDMEGVIEAD-SDPAQPMGNYSKKATE- 120

  Fly    82 QDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAVYPHDPIYHINRALCYLKQESF 146
                     ::.::|::::.:..:...|.::::||..|:.||.:.|.:.::|..|...:||.:..
  Fly   121 ---------EEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKP 176

  Fly   147 DQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIEPKNIEAKRSLARINDRL 211
            :.|:.||:.|:.|:......|..|.:|...||:...|..|......:: .:.|....|..:....
  Fly   177 NACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLD-FDEETDEWLKEVTPNA 240

  Fly   212 RKIATKSGPNFTPDRPGMIEILPIEKPAYKRSKKAMRSVPVVDVVSPRATIDDSNQLRISDEDID 276
            :|                     ||:...|:.::.          :.|...:.....|.:.::.:
  Fly   241 KK---------------------IEQHRLKQERRQ----------AERKIKERQRDQRRARKEQE 274

  Fly   277 KIFNSNCGIIEEVKKTNPKPTPMPDTSGPPKAETIAKTSKEVKPTKQTAVKVAPAVETPKETETR 341
            |...|:.|...|....||....|.|..|......::...:::........|.|   ..||.....
  Fly   275 KHNASSGGSSGEFSGGNPGNGNMSDILGAMSDPEVSAAIQDILSNPGNITKYA---SNPKIYNLI 336

  Fly   342 KDTKIVPESD----------NEAKPSAPK 360
            |  ||||..|          ...|||.||
  Fly   337 K--KIVPGGDVGAAFGQAGEKAGKPSEPK 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spagNP_524664.1 TPR_11 95..161 CDD:290150 17/65 (26%)
TPR repeat 96..124 CDD:276809 6/27 (22%)
TPR_1 102..129 CDD:278916 7/26 (27%)
TPR repeat 129..159 CDD:276809 8/29 (28%)
TPR 130..160 CDD:197478 8/29 (28%)
TPR_16 136..197 CDD:290168 15/60 (25%)
TPR repeat 164..192 CDD:276809 7/27 (26%)
RPAP3_C 415..503 CDD:290588
HIP-RNP_001014719.2 Hip_N 10..47 CDD:271228
TPR_11 125..190 CDD:290150 16/64 (25%)
TPR_2 126..159 CDD:285020 8/32 (25%)
TPR repeat 126..154 CDD:276809 6/27 (22%)
TPR repeat 159..189 CDD:276809 8/29 (28%)
TPR repeat 194..222 CDD:276809 7/27 (26%)
STI1 299..336 CDD:128966 6/39 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45462431
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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