Protein Alignment spag and Unc45a

DIOPT Version :10

• Sequence 1: NP_524664.1
• Gene: spag / 43958
• FlyBaseID: FBgn0015544
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_598713.2
• Gene: Unc45a / 101869
• MGIID: 2142246
• Length: 944
• Species: Mus musculus
• Alignment Length: 211
• Identity: 67/211 - (31%)
• Similarity: 97/211 - (45%)
• Gaps: 23/211 - (10%)

  Fly    76 SSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAV--YPHD-PIYHINRA 137
            |.|...:..|.||.|   ..|..::..||...|.|:||.|:.||:.|:::  .|.| .|.|.|||
Mouse     4 SGPETPEPRPSDPGA---SSAEQLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAILHRNRA 65

  Fly   138 LCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIEPKNIEAKR 202
            .|:||.|.:.:...:...||..|...|||.|||.||.|.||...:|:.|....:::||||...:.
Mouse    66 ACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQE 130

  Fly   203 SLARINDRLR-KIATKSGPNFTPDRPGMIEILPIEKPAYKRSKKAMRSVPVVDVVSPRATIDDSN 266
            ||..|..::: |:...|..:...::...|.:.|.||...|:.|.:...|
Mouse   131 SLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLV---------------- 179

  Fly   267 QLRISDEDIDKIFNSN 282
            .|...|...:|||.||
Mouse   180 VLAREDAGAEKIFRSN 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spag	NP_524664.1	TPR repeat	96..124	CDD:276809	11/27 (41%)
		TPR	102..>211	CDD:440225	44/111 (40%)
		TPR repeat	129..159	CDD:276809	12/30 (40%)
		TPR repeat	164..192	CDD:276809	13/27 (48%)
		PLN03209	<296..416	CDD:178748
		RPAP3_C	416..503	CDD:464012
Unc45a	NP_598713.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		7/23 (30%)
		NlpI	<21..>125	CDD:443815	40/103 (39%)
		TPR 1	21..54		11/32 (34%)
		TPR repeat	21..49	CDD:276809	11/27 (41%)
		TPR repeat	57..87	CDD:276809	11/29 (38%)
		TPR 2	58..91		12/32 (38%)
		TPR 3	92..125		15/32 (47%)
		TPR repeat	92..120	CDD:276809	13/27 (48%)
		UNC45-central	361..505	CDD:432011