DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cds and cdgs-1

DIOPT Version :9

Sequence 1:	NP_001286976.1	Gene:	Cds / 43950	FlyBaseID:	FBgn0010350	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_501298.1	Gene:	cdgs-1 / 3565046	WormBaseID:	WBGene00016384	Length:	465	Species:	Caenorhabditis elegans

Alignment Length:	459	Identity:	249/459 - (54%)
Similarity:	321/459 - (69%)	Gaps:	27/459 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEVRRRKGEDEPLEDTAISGSDAANKRNSAADSSDHVDSE----------EEKIPEEKFVDELAK 56
            |:||:|:..:.|:.:..     .|..|:.|..:||..|.|          ..|..||| ::.|.:
Worm    10 ADVRQRRAPESPVTERL-----RAPARDDARPTSDESDMEGILQDEDSDAGSKNKEEK-LERLTQ 68

  Fly    57 NLPQGTDKTPEILDSALKDLPDRWKNWVIRGIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQ 121
            .:||.........||.|:.||.||:|||:||:|:.|||..|..|:..|...||....|:|.||||
Worm    69 AIPQDKGSLGVFADSMLEALPPRWRNWVVRGLFSIIMISTFTFIVTRGATWLMFLVFLIQFKCFQ 133

  Fly   122 EIISIGYQVYRIHGLPWFRSLSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFA 186
            ||||||..|||::..||||:|||||||||||||:||:|:||:|:|:.:..:|.|||.|||.:|||
Worm   134 EIISIGLAVYRLYDFPWFRALSWYFLLTSNYFFFGESLIDYWGIVLKKDNFLHFLVAYHRLVSFA 198

  Fly   187 LYIIGFVWFVLSLVKKYYIKQFSLFAWTHVSLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDV 251
            ||.||||.|||||.|.||::|||||||||::||::|:||:.||||||:|||||:.||:||:|.|:
Worm   199 LYCIGFVSFVLSLRKGYYMRQFSLFAWTHLTLLLIVSQSFFIIQNIFQGLIWFLAPVAMIICCDI 263

  Fly   252 MAYVFGFFFGRTPLIKLSPKKTWEGFIGGGFATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTM 316
            |:|:||||:|:||||||||||||||||||.|:||:||||.|..|.|..:|:||:|:.:..   :.
Worm   264 MSYMFGFFWGKTPLIKLSPKKTWEGFIGGAFSTVVFGILLSLALYNRPFFVCPVQHYQTD---SS 325

  Fly   317 SCVPSYLFTPQEYSL--------KLFGIGKTLNLYPFIWHSISLSLFSSIIGPFGGFFASGFKRA 373
            :|.....|..|:|.:        |:......:.|.||::|||:||||:||:||||||||||||||
Worm   326 NCTIPLAFQLQDYPVPRPFSFVYKILRKEPIIQLCPFVFHSIALSLFASILGPFGGFFASGFKRA 390

  Fly   374 FKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVYISSFIRTPSPAKLLTQIYNLKPDQQYQIYQSL 438
            ||||||||:||||||:|||||||.||.|||.|||.||||.|..:|||.||..|:|..|..|:..|
Worm   391 FKIKDFGDVIPGHGGLMDRFDCQLLMGTFVMVYIHSFIRVPDASKLLKQIMTLEPQDQLNIFNLL 455

  Fly   439 KDNL 442
            :..|
Worm   456 QSEL 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cds	NP_001286976.1	CTP_transf_1	120..438	CDD:304393	203/325 (62%)
cdgs-1	NP_501298.1	CTP_transf_1	147..443	CDD:304393	188/298 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167925
Domainoid	1	1.000	436	1.000	Domainoid score	I285
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68173
Inparanoid	1	1.050	498	1.000	Inparanoid score	I759
Isobase	1	0.950	-	0	Normalized mean entropy	S804
OMA	1	1.010	-	-		QHG54574
OrthoDB	1	1.010	-	-		D1072976at2759
OrthoFinder	1	1.000	-	-		FOG0001281
OrthoInspector	1	1.000	-	-		oto18515
orthoMCL	1	0.900	-	-		OOG6_101561
Panther	1	1.100	-	-	LDO	PTHR13773
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2065
SonicParanoid	1	1.000	-	-		X636
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890