DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cds and SPBC13A2.03

DIOPT Version :9

Sequence 1:	NP_001286976.1	Gene:	Cds / 43950	FlyBaseID:	FBgn0010350	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_596416.1	Gene:	SPBC13A2.03 / 2540017	PomBaseID:	SPBC13A2.03	Length:	439	Species:	Schizosaccharomyces pombe

Alignment Length:	429	Identity:	182/429 - (42%)
Similarity:	259/429 - (60%)	Gaps:	28/429 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NKRNSAADSSDHVDSEEEKIPEEKFVDELAKNLPQGTDKTPE----ILDSALKDLPDRWKNWVIR 86
            ||||::...:.:|.              :.:|....:.||.|    ....:|...|.  :|::.|
pombe     7 NKRNNSDKENGNVG--------------VVQNKDSASSKTTEPARLTKHKSLARKPS--QNFITR 55

  Fly    87 GIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQEIISIGYQVYRIHGLPWFRSLSWYFLLTSN 151
            .|:|::::..|...:..|...:::...:||:..::|:|:|.....|...|||.|.::||||:|:.
pombe    56 TIWTFLLLGIFFTALAMGHFWVVLLVTIVQIGVYKEVIAIASVPSREKDLPWTRFINWYFLMTTL 120

  Fly   152 YFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYIIGFVWFVLSLVKKYYIKQFSLFAWTHV 216
            |:.|||::..||..:.....::..||.:|||:||.|||||||.||.||.|..|..|||.|.|||:
pombe   121 YYAYGESIYAYFHHLFIMDSFMLPLVLHHRFISFMLYIIGFVLFVASLKKGNYKFQFSQFCWTHM 185

  Fly   217 SLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDVMAYVFGFFFGRTPLIKLSPKKTWEGFIGGG 281
            :||:||.||:.:|.|:||||.||.|||..:|||||.||:.|..||:.|||::|||||.|||:||.
pombe   186 TLLLVVGQSHFMINNLFEGLFWFFVPVCYVVCNDVFAYLCGKMFGKHPLIQVSPKKTVEGFLGGW 250

  Fly   282 FATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTMSCVPSYLFTPQEYSL-----KLFGIGKTLN 341
            ..||:.|.|.||||.:::|||||.:.........::|.|:.:|.|..|::     ..|.:.:|:.
pombe   251 ICTVVIGSLISYVLMHFKYFICPTRDLSTSAFSGLNCTPNSVFLPHTYTIPAVFVDTFRLPETIT 315

  Fly   342 LYPFIWHSISLSLFSSIIGPFGGFFASGFKRAFKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVY 406
            |.|..:|....:.|||:|.|||||||||.||||||||||..||||||:.||.|||||...||.:|
pombe   316 LAPIYFHLAIFATFSSLIAPFGGFFASGLKRAFKIKDFGASIPGHGGLTDRMDCQFLNGVFVYMY 380

  Fly   407 ISSFI--RTPSPAKLL-TQIYNLKPDQQYQIYQSLKDNL 442
            ..|||  ::.|.|.|| |.:|:|...||.|:.:.|::.|
pombe   381 FQSFIAEKSTSVADLLDTAVYSLTTTQQVQLVEDLQNYL 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cds	NP_001286976.1	CTP_transf_1	120..438	CDD:304393	161/325 (50%)
SPBC13A2.03	NP_596416.1	CTP_transf_1	86..424	CDD:304393	163/334 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	316	1.000	Domainoid score	I237
eggNOG	1	0.900	-	-		E1_COG0575
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68173
Inparanoid	1	1.050	333	1.000	Inparanoid score	I511
OMA	1	1.010	-	-		QHG54574
OrthoFinder	1	1.000	-	-		FOG0001281
OrthoInspector	1	1.000	-	-		oto101528
orthoMCL	1	0.900	-	-		OOG6_101561
Panther	1	1.100	-	-	LDO	PTHR13773
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2065
SonicParanoid	1	1.000	-	-		X636
TreeFam	1	0.960	-	-
	14	13.860