| Sequence 1: | NP_723870.1 | Gene: | wb / 43946 | FlyBaseID: | FBgn0261563 | Length: | 3375 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002284.3 | Gene: | LAMC1 / 3915 | HGNCID: | 6492 | Length: | 1609 | Species: | Homo sapiens |
| Alignment Length: | 1598 | Identity: | 424/1598 - (26%) |
|---|---|---|---|
| Similarity: | 628/1598 - (39%) | Gaps: | 449/1598 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 155 PPLFNVVPRAQISVNATCGQNGAEEYCKQVG----AKPCGICNAHSSDRAKQRSIQSLISSGSGS 215
Fly 216 GSGSGF--------EEGWWQSPTLQGGRQF-EYVTILLDLKQTFQIFSVWLKSANSPRPASWILE 271
Fly 272 KSL--DGINFEPW---QYFGLSDADCQRRWNLSGQNGKYVFQNDTEIICSTQFSKPGPLENGVLH 331
Fly 332 ASLLKNRPGA--TDQSPELMKFITTRYIRIRLQGMHSTANQDNSL-DWLLDSPSLEKHSFYSLSQ 393
Fly 394 LKVSARLDCNGHANRSHESPDDPLMQCICQHNTCGAQCEQCCPLFQDRPY-----QMGGECEICQ 453
Fly 454 CYGHAESCTYDPFLDK-----GICQSCSNNTAGIECEFCEMGFYRELDAPLTDPCLPCSCNPARS 513
Fly 514 TGGCQSDGGSCNCLEGFQGKNCEECAPGYYG---DDCKRCECDERGSLGSTGSCSGVCQCKLNVE 575
Fly 576 GSTCSECAPGYFDLSAENAEGCTSCWCSGVSQTC-----HSAKLQTLAFETLND-WKITDIQRVK 634
Fly 635 PISIPVDAETNRLIFANELDEVEAI-------YWQASLGYLGNRLTSYGSRLQLVLSWDVIRGDR 692
Fly 693 SGKPTTGPNVILVGKNGLKIAFGDESLDGLGINLNVTLTEVGWYHVPPTVVDIKTRLRRTEGGDY 757
Fly 758 HGE-SVTRSQFLSVLVSLDAVLIRAAFHTDQGETSLERAVIYSGGVELG------GKSSSQVEQC 815
Fly 816 LCPAGYTGLSCEGCAFGFKRIYENTSDHQILSKCIPCPCNGHSNSCDLQSGNCGDCMHNTFGDRC 880
Fly 881 ERCQLGYYGNPLQGTPNDCKRCACPLSEDSNNFSPSCQLKSYNYMDLNPQFELIEHAEYICTQCP 945
Fly 946 EGYTGDHCQVCDDGYFGNP---RQPGSSCQRCDC-------AGGPCNVTTGECITCRGNTEGWHC 1000
Fly 1001 ERCKLGYWGDPAVGCDPCHCHTEGSESGLCDSTDGQCLCKPRYAGQKCDECDVGYANVELRCPSC 1065
Fly 1066 NCDPLGSLVQDRCDPHTGQCHCKEGVMGAKCHECQDGYFGMNAVAYRMDDLAALRQNSDSDDDEW 1130
Fly 1131 ELVPDTEDPNSESTVACEECHCSSVGSLSSDCDKRTGQCACLANVTGRRCDKCRPGHWNLTAGEG 1195
Fly 1196 CRDCRCDPHGSRGHECNPWTGQCDCKIGVGGQHCNECTEGFFGFSTEGCQRCSACRSEGQVCDPH 1260
Fly 1261 NGRCICPKFTRGLGCGQCVPGTWGWQARLGCRECECDHIGSIGQQCSTGDGQCQCREGYSGRKCD 1325
Fly 1326 TCAIGYF---GYPECRRC-GCDAEGSFTQADGSIACDSNGQCPCKSLVVGLKCDTCMQSTFGLSA 1386
Fly 1387 QNPEGCTRCFCFGRSGECEQSDLSWGHIRMAE-----SRNLSVQQIRPHSVPSSDYEYIVVVQ-- 1444
Fly 1445 -------MEGSSFHREDAEIQRM-----NDLSLVPKSTGNVSIGAYGQFYHPLYFQLPPQFYGDR 1497
Fly 1498 TSSYGGFLYFTLITEGAHKPLERNILGQYPLVQL---------HAHSKLLLDF-------YEYEE 1546
Fly 1547 ----FEYSLNVTHRVP-----LHESFWK--------YHHTSQ--AVDRNTLMAALQNIRHIFIRA 1592
Fly 1593 FAFADFQEVVLQNV--HMDAAIYIKGS----TNLIAKG 1624 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| wb | NP_723870.1 | Laminin_N | 164..396 | CDD:278484 | 69/252 (27%) |
| EGF_Lam | 401..450 | CDD:238012 | 22/53 (42%) | ||
| TNFRSF | <407..507 | CDD:304602 | 37/109 (34%) | ||
| EGF_Lam | 505..552 | CDD:238012 | 15/49 (31%) | ||
| Laminin_EGF | 550..597 | CDD:278482 | 20/46 (43%) | ||
| Laminin_B | 660..798 | CDD:278481 | 33/138 (24%) | ||
| EGF_Lam | 851..900 | CDD:238012 | 24/48 (50%) | ||
| Laminin_EGF | <943..971 | CDD:278482 | 15/30 (50%) | ||
| VSP | 953..1414 | CDD:146106 | 115/474 (24%) | ||
| Laminin_EGF | 974..1018 | CDD:278482 | 21/50 (42%) | ||
| EGF_Lam | 1017..1065 | CDD:238012 | 2/47 (4%) | ||
| Laminin_EGF | 1065..>1105 | CDD:278482 | 5/39 (13%) | ||
| EGF_Lam | 1150..1197 | CDD:238012 | 19/46 (41%) | ||
| Laminin_EGF | 1199..1247 | CDD:278482 | 20/47 (43%) | ||
| EGF_Lam | 1247..1292 | CDD:238012 | 1/44 (2%) | ||
| Laminin_EGF | 1294..1342 | CDD:278482 | 22/51 (43%) | ||
| Laminin_EGF | 1340..1392 | CDD:278482 | 9/52 (17%) | ||
| Laminin_B | 1486..1611 | CDD:278481 | 30/161 (19%) | ||
| EGF_Lam | 1669..1716 | CDD:238012 | |||
| Laminin_EGF | 1718..1767 | CDD:278482 | |||
| EGF_Lam | 1772..1819 | CDD:238012 | |||
| CrfC | <1933..2267 | CDD:223771 | |||
| Laminin_II | 2277..2400 | CDD:283628 | |||
| LamG | 2399..>2492 | CDD:304605 | |||
| Laminin_G_2 | 2616..2755 | CDD:280389 | |||
| Laminin_G_2 | 2804..2944 | CDD:280389 | |||
| Laminin_G_2 | 3038..3169 | CDD:280389 | |||
| LamG | 3192..3347 | CDD:238058 | |||
| LAMC1 | NP_002284.3 | Domain VI | 34..285 | 72/264 (27%) | |
| LamNT | 44..284 | CDD:214532 | 72/263 (27%) | ||
| EGF_Lam | 285..330 | CDD:238012 | 22/45 (49%) | ||
| Domain V | 286..509 | 84/226 (37%) | |||
| Laminin_EGF | 342..396 | CDD:278482 | 18/56 (32%) | ||
| Laminin_EGF | 398..445 | CDD:278482 | 14/46 (30%) | ||
| Laminin_EGF | 445..492 | CDD:278482 | 20/46 (43%) | ||
| Domain IV | 510..689 | 48/218 (22%) | |||
| LamB | 553..678 | CDD:214597 | 36/154 (23%) | ||
| Domain III | 690..1030 | 154/536 (29%) | |||
| EGF_Lam | 724..771 | CDD:238012 | 24/47 (51%) | ||
| EGF_Lam | 772..820 | CDD:238012 | 22/67 (33%) | ||
| Laminin_EGF | 828..875 | CDD:278482 | 21/88 (24%) | ||
| EGF_Lam | 883..933 | CDD:238012 | 24/132 (18%) | ||
| EGF_Lam | 935..980 | CDD:214543 | 20/91 (22%) | ||
| EGF_Lam | 982..1029 | CDD:238012 | 20/47 (43%) | ||
| Domain I/II | 1031..1609 | 64/346 (18%) | |||
| t_SNARE | 1072..1155 | CDD:197699 | 18/99 (18%) | ||
| MA | 1091..1302 | CDD:214599 | 42/238 (18%) | ||
| MCP_signal | 1123..1255 | CDD:304920 | 28/153 (18%) | ||
| V_Alix_like | 1180..>1336 | CDD:187408 | 30/155 (19%) | ||
| Laminin_I | 1287..1530 | CDD:283627 | 9/48 (19%) | ||
| SH3BP5 | 1361..1592 | CDD:283045 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1836 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||