DRSC/TRiP Functional Genomics Resources

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Protein Alignment wb and Ntng1

DIOPT Version :10

Sequence 1:NP_723870.1 Gene:wb / 43946 FlyBaseID:FBgn0261563 Length:3375 Species:Drosophila melanogaster
Sequence 2:NP_001099935.1 Gene:Ntng1 / 295382 RGDID:1563465 Length:539 Species:Rattus norvegicus


Alignment Length:482 Identity:138/482 - (28%)
Similarity:205/482 - (42%) Gaps:95/482 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   171 TCGQNGAEEYCKQVGAKPC-GICNAHSSDRAKQRSIQSLISSGSGSGSGSGFE-EG-----WWQS 228
            ||| :..|.:|.......| ..|:|.:.:.|....:.              |: ||     :|||
  Rat    71 TCG-DPPESFCAMGNPYMCNNECDASTPELAHPPELM--------------FDFEGRHPSTFWQS 120

  Fly   229 PTLQGGRQFEY-----VTILLDLKQTFQIFSVWLKSANSPRPASWILEKSLD-GINFEPWQYFGL 287
            .|.:     ||     |.|.|...:|.::....:.:..|.||...||||||| |..::|:||:. 
  Rat   121 ATWK-----EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA- 179

  Fly   288 SDADCQRRWNLSGQNGKYVFQNDT-EIICSTQFSKPGPLENGVLHASL-----------LKNRP- 339
              .||...:::..::.|.:.|:.. ||||:.::|......:.::|..:           |:|.. 
  Rat   180 --TDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMAS 242

  Fly   340 --GATDQSPELMKFITTRYIRIRLQGMHSTANQDNSLDWLLDSPSLEKHSFYSLSQLKVSARLDC 402
              |..|.:.:|..|.|...:||||  :.....     :..:|...|.:: ||::|.:||..|..|
  Rat   243 LYGQLDTTKKLRDFFTVTDLRIRL--LRPAVG-----EIFVDELHLARY-FYAISDIKVRGRCKC 299

  Fly   403 NGHANRSHESPDDPLMQCICQHNTCGAQCEQCCPLFQDRPYQMGGECEI---------------- 451
            |.||...  ..|:..:.|.|:|||.|..|.:|...:|.||:..|....|                
  Rat   300 NLHATMC--VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIG 362

  Fly   452 -CQCYGHAESCTYDPFLDKGICQSCSNNTAGIECEFCEMGFYRELDAPLTDP--CLPCSCNPARS 513
             |:|:||:..|:|...|:..||.||.:||.|..||.|.:|::|...|.|.|.  |:.|.|||..|
  Rat   363 NCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGS 427

  Fly   514 TGGCQSDGGSCNCLEGFQGKNCEECAPG---YYGDDCKRCECD-ERGSLGSTGSCSGVCQCKLNV 574
            .....:..|.|.|..|..|..|:||.||   |||  |:...|| |.....:.|:|....:|    
  Rat   428 IHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYG--CQPNVCDNELLHCQNGGTCHNNVRC---- 486

  Fly   575 EGSTCSECAPGYF--DLSAENAEGCTS 599
               .|.:...|..  .|..|.|..|.|
  Rat   487 ---VCPDAYTGILCEKLRCEEAGSCGS 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wbNP_723870.1 Laminin_N 153..398 CDD:459653 64/254 (25%)
EGF_Lam 401..450 CDD:238012 17/48 (35%)
EGF_Lam 505..552 CDD:238012 19/49 (39%)
Laminin_EGF 550..597 CDD:395007 11/49 (22%)
Laminin_B 660..813 CDD:459652
EGF_Lam 851..900 CDD:238012
Laminin_EGF <943..971 CDD:395007
Laminin_EGF 974..1018 CDD:395007
EGF_Lam 1017..1065 CDD:238012
Laminin_EGF 1065..>1105 CDD:395007
EGF_Lam 1150..1197 CDD:238012
Laminin_EGF 1199..1247 CDD:395007
EGF_Lam 1247..1292 CDD:238012
Laminin_EGF 1294..1342 CDD:395007
Laminin_EGF 1340..1392 CDD:395007
Laminin_B 1486..1626 CDD:459652
EGF_Lam 1669..1716 CDD:238012
Laminin_EGF 1718..1767 CDD:395007
EGF_Lam 1772..1819 CDD:238012
YhaN <1907..2141 CDD:443752
SMC_prok_B <2123..>2390 CDD:274008
Laminin_II 2279..2400 CDD:368703
LamG 2399..>2492 CDD:473984
LamG 2586..2753 CDD:238058
Laminin_G_2 2804..2944 CDD:460494
LamG 3018..3167 CDD:238058
LamG 3192..3347 CDD:238058
Ntng1NP_001099935.1 Laminin_N 50..295 CDD:459653 64/254 (25%)
EGF_Lam 296..342 CDD:238012 17/47 (36%)
EGF_Lam 364..412 CDD:238012 20/47 (43%)
EGF_Lam 420..467 CDD:214543 19/48 (40%)
EGF_CA <474..498 CDD:238011 5/30 (17%)
Blue background indicates that the domain is not in the aligned region.

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