DRSC/TRiP Functional Genomics Resources

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Protein Alignment wb and ntng1

DIOPT Version :10

Sequence 1:NP_723870.1 Gene:wb / 43946 FlyBaseID:FBgn0261563 Length:3375 Species:Drosophila melanogaster
Sequence 2:XP_031756887.1 Gene:ntng1 / 100494090 XenbaseID:XB-GENE-981283 Length:541 Species:Xenopus tropicalis


Alignment Length:496 Identity:119/496 - (23%)
Similarity:189/496 - (38%) Gaps:142/496 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 NATCGQNGAEEYCKQVGAKPC-GICNAHSSDRAKQRSIQSLISSGSGSGSGSGFEEGWWQSPTLQ 232
            ::||| :..|.:|.......| ..|:|::.:.|....:...:...:.|        .:|||.|.:
 Frog    65 DSTCG-DPPEAFCAMGNPYMCNNECDANTQELAHPPDLMFDVEGRNPS--------TFWQSKTWK 120

  Fly   233 GGRQFEYVTILLDLKQTFQIFSVWLKSANSPRPASWILEKSLD-GINFEPWQYFGLSDADCQRRW 296
            ...:...|.|.|...:|.::.:....:..|.||...:|||||| |..::|:|::.   |||...:
 Frog   121 HYPKPLQVNITLSWNKTIELTNNVAITFESGRPEKMVLEKSLDYGRTWQPYQFYA---ADCLDAF 182

  Fly   297 NLSGQNGKYVFQNDT-EIICSTQFSK--------------------PGPLENGVLH--ASLLKNR 338
            .:..::.|.:..:.. :|||:.::|.                    .||.    ||  |||... 
 Frog   183 RMEPKSVKDLTHSTVLDIICTEEYSTGYAAHAKTLSFEIKDRFAIFAGPR----LHNMASLYSQ- 242

  Fly   339 PGATDQSPELMKFITTRYIRIRLQGMHSTANQDNSLDWLLDSPSLEKHSFYSLSQLKVSARLDCN 403
               .|.:..|..|.|...:||||....:.|.       .:|..:|.:: ||::|.:|:..|..||
 Frog   243 ---LDTTKNLRDFFTVTDLRIRLLKPATGAT-------FVDEKNLGRY-FYAISDIKIHGRCKCN 296

  Fly   404 GHANRSHESPDDPLMQCICQHNTCGAQCEQCCPLFQ----------------------------- 439
            .|||..  :..:..:.|.|:|||.|..|::|...||                             
 Frog   297 LHANSC--TFTNNRLACDCEHNTTGQDCDKCKKNFQGQAWSPGSYLTIPKGTANICVSSIPSTVQ 359

  Fly   440 ---------------DR--------------------------PYQMGGECEICQCYGHAESCTY 463
                           ||                          |.|:......|.|:||:..|||
 Frog   360 DKKKKQSITTAPPNFDRIKTNSSFLDVANRKQVFSKLALSTVSPAQVSSHKRDCYCHGHSNRCTY 424

  Fly   464 DPFLDKGICQSCSNNTAGIECEFCEMGFYRELDAPLTD--PCLPCSCNPARSTGGCQSDGGSCNC 526
            ...::..:|.||.:||.|.:||.|:.||:|...|.|.|  .|:...|:  .....||:||...|.
 Frog   425 IEVVNTAVCVSCRHNTRGQQCEKCKKGFHRNGSAKLDDVNVCIANVCD--NELLRCQNDGVCYNN 487

  Fly   527 LEGFQGKNCEECAPGYYGDDCKRCECDERGSLGSTGSCSGV 567
            :      .| .|..||.|..|::.:|      ..||.|..:
 Frog   488 I------RC-HCPSGYTGILCEKQKC------ADTGDCDSI 515

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wbNP_723870.1 Laminin_N 153..398 CDD:459653 60/253 (24%)
EGF_Lam 401..450 CDD:238012 19/118 (16%)
EGF_Lam 505..552 CDD:238012 12/46 (26%)
Laminin_EGF 550..597 CDD:395007 4/18 (22%)
Laminin_B 660..813 CDD:459652
EGF_Lam 851..900 CDD:238012
Laminin_EGF <943..971 CDD:395007
Laminin_EGF 974..1018 CDD:395007
EGF_Lam 1017..1065 CDD:238012
Laminin_EGF 1065..>1105 CDD:395007
EGF_Lam 1150..1197 CDD:238012
Laminin_EGF 1199..1247 CDD:395007
EGF_Lam 1247..1292 CDD:238012
Laminin_EGF 1294..1342 CDD:395007
Laminin_EGF 1340..1392 CDD:395007
Laminin_B 1486..1626 CDD:459652
EGF_Lam 1669..1716 CDD:238012
Laminin_EGF 1718..1767 CDD:395007
EGF_Lam 1772..1819 CDD:238012
YhaN <1907..2141 CDD:443752
SMC_prok_B <2123..>2390 CDD:274008
Laminin_II 2279..2400 CDD:368703
LamG 2399..>2492 CDD:473984
LamG 2586..2753 CDD:238058
Laminin_G_2 2804..2944 CDD:460494
LamG 3018..3167 CDD:238058
LamG 3192..3347 CDD:238058
ntng1XP_031756887.1 Laminin_N 46..291 CDD:459653 60/253 (24%)
EGF_Lam 292..338 CDD:238012 16/47 (34%)
EGF_Lam 413..461 CDD:238012 20/47 (43%)
EGF_CA <478..502 CDD:238011 10/30 (33%)
Blue background indicates that the domain is not in the aligned region.

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