Protein Alignment sbr and nxf1a

DIOPT Version :10

• Sequence 1: NP_524660.1
• Gene: sbr / 43944
• FlyBaseID: FBgn0003321
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_073777740.1
• Gene: nxf1a / 751719
• ZFINID: ZDB-GENE-060825-299
• Length: 659
• Species: Danio rerio
• Alignment Length: 590
• Identity: 180/590 - (30%)
• Similarity: 297/590 - (50%)
• Gaps: 104/590 - (17%)

  Fly   113 WYQVTLQNAQI-----------------YEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDD 160
            |:::||...|:                 |:|..||:: |..:.|..|.|.::..|.:.|.|:.:|
Zfish   144 WFKMTLCFLQLLDASRVPLKQPIPHGKKYDKRWLLTS-LQNLCPIAFTPLHYTTEGDKVHFYLED 207

  Fly   161 YEAAERIQHLGKNGHLPDGYRLM---------PRVRSGIPLVAIDDAFKEKMKVTMAKRYNIQTK 216
            ...|..:..|.:.....||.|::         |.::|.:.|..:     |.:|:.::||::...|
Zfish   208 TTTASALSKLSRRILDSDGQRVVVLMNSCYFPPFLKSELRLEDL-----ELLKLCLSKRFDDSQK 267

  Fly   217 ALDLSRFHADPDL--KQVFCPLFRQNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRL 279
            :|||:....||:|  ..|...|.|:|.|.|.|.|:.::||:|.:|||:.|.:..::....:..:.
Zfish   268 SLDLTSIRTDPELVSHNVDIILNRKNCMQAVIKIIQESIPELLSLNLSKNKLYKLDGLTELVNKA 332

  Fly   280 PNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGET 344
            |||:.|.|..|::.|...|..::...::||.|..||...|:||...:||.|::.||:|::|||..
Zfish   333 PNLQSLNLSCNELKSHCELDKVKGFRLVELCLDGNPLCDRFKDQTTYISAVQKCFPRLLRLDGHV 397

  Fly   345 LEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISM 409
            |...|.|::.....:...|.|:........::::||:||:.|:|||:||.||:||||.|..|:.:
Zfish   398 LSLPICFEVETSSNIPLCKGSHFVSNEIQGLIQRFLEQYYSIYDSGDRQPLLEAYHESACFSLCL 462

  Fly   410 PSASQAGRLN-SFWKFNRNLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIY 473
            ||.|...|.. .::|.:||::. :.....|.|.||:.||..|:.|:|.||||||..:..||:..|
Zfish   463 PSISNPSRYKLDYFKNSRNVKN-IKDSPTRFRLLKHTRLTVVACLNELPKTQHDINSINVDVNAY 526

  Fly   474 NTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVP-QNNGFCIRNETIFITNATHEQV 537
            .::::.|||:|:|||::|:     |.:|:  :.|:|.:|.|| ||:|.||.|:.:|:.|.|.|::
Zfish   527 ASTLLAFTVSGVFKEVDDQ-----SEDLF--KAFSRVFVTVPAQNSGLCIVNDELFVRNTTMEEI 584

  Fly   538 REFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGS 602
            :                  .|.|:|....             ::.||.|||
Zfish   585 Q------------------CAFTTPTQSP-------------SSSPVPILS-------------- 604

  Fly   603 AAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPP 667
                           :.:.:|:.|.|..|:||:.||:||||:..|||..||.:|.:|.....||.
Zfish   605 ---------------AYQQEMLSAFSQMSEMNLQWSQKCLEDNAWDFQQAAQIFAELQAHGMIPE 654

  Fly   668 EAFMK 672
            .||:|
Zfish   655 AAFIK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbr	NP_524660.1	Tap-RNA_bind	113..191	CDD:462696	23/103 (22%)
		leucine-rich repeat	215..255	CDD:275382	16/41 (39%)
		LRR	<252..>315	CDD:443914	18/62 (29%)
		leucine-rich repeat	256..281	CDD:275382	5/24 (21%)
		leucine-rich repeat	282..305	CDD:275382	6/22 (27%)
		leucine-rich repeat	306..336	CDD:275382	12/29 (41%)
		NTF2	372..531	CDD:238403	65/160 (41%)
		flgK	<548..>613	CDD:235895	8/64 (13%)
		TAP_C	609..671	CDD:197882	22/61 (36%)
nxf1a	XP_073777740.1	None