Protein Alignment sbr and nxf1

DIOPT Version :10

• Sequence 1: NP_524660.1
• Gene: sbr / 43944
• FlyBaseID: FBgn0003321
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_031756030.1
• Gene: nxf1 / 734058
• XenbaseID: XB-GENE-489552
• Length: 627
• Species: Xenopus tropicalis
• Alignment Length: 708
• Identity: 223/708 - (31%)
• Similarity: 332/708 - (46%)
• Gaps: 132/708 - (18%)

  Fly    16 VGNGGGRYNAPEDF-------DD-----FDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPED 68
            :|.|..|   ||:.       ||     |.::.|:.|.....:..|..|.: ..||......|..
 Frog     1 MGKGLAR---PEEITLTRTEHDDRYGGGFSMKKRKGRGPFMGKMYSEGPHK-YRNKGGYGPNPRS 61

  Fly    69 LRRWDEDDDMSDMTTAVKD-RPTSRRRGSPIPRG------KFGKLMPNSFG-------------- 112
             |..|:|.|:     |:.| ..:||.|..|..||      |.|:...| ||
 Frog    62 -RLEDDDGDV-----AMGDAHESSRHRFVPYGRGGKRRDEKPGRDKKN-FGGSHREPQQQGRAEY 119

  Fly   113 ------WYQVTLQNAQIYEKETLLSALLAAMS-PHVFIPQYWRVERNCVIFFTDDYEAAERIQHL 170
                  |::||:.:.:.|||..||..|..|.| |  |.|.::..:.|...||.:|..||:.::.|
 Frog   120 SEDRKSWFKVTIPHGKKYEKSWLLGILQGASSVP--FNPVHYHTDHNRAHFFVEDSAAAKALKQL 182

  Fly   171 GKNGHLPDGYRLMPRVRSGIP----LVAIDDAFKEKMKVTMAKRYNIQTKALDLSRFHADPDL-- 229
            .:.....:.:::....|...|    ...|.|...|..|..|.|||:...:|||:....:||||
 Frog   183 SRTFTDRENFKITILTRPCPPPQNFTKEIKDEELEHFKNCMQKRYDGAHQALDMKAVRSDPDLVA 247

  Fly   230 KQVFCPLFRQNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPS 294
            .:|...|.|:..|...:.|:.||:|:|.:|::::|.:..::..:.:..:.||||||.|..|.:.|
 Frog   248 NKVDLILNRKCYMTTMLQIIEDNVPELLSLDISNNKLYKLDDLEEITLKAPNLKILNLSQNLLKS 312

  Fly   295 LAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRL 359
            ...|..::.|.:.||.|..||....::|...:||.||.:||||::|||..|.|.||||:.....|
 Frog   313 DRELDKVKGLKLEELWLDGNPLCDTFRDQTNYISAVRERFPKLLRLDGHELPPPITFDVETPTTL 377

  Fly   360 LETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPS----ASQAGRLNS 420
            ...|.|||.......:|.:||.||:..:||.:||.||:.||::|..|:|:||    ......|..
 Frog   378 PPCKGSYLASDDIKALVLRFLQQYYACYDSEDRQGLLNVYHDEACCSLSIPSNPGQNPSRSSLGE 442

  Fly   421 FWKFNRNLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGL 485
            ::|.:||:|| |.....|.:.||:.||..|..|:|.|:||||..:|.||:|.::.:::.|.|.|:
 Frog   443 YFKDSRNIRR-LRDPTLRFKLLKHKRLNVVGFLNELPRTQHDLNSFVVDITAHSNTLLCFVVNGI 506

  Fly   486 FKELNDETNNPASMELYDVRHFARTYVVVP-QNNGFCIRNETIFITNATHEQVREFKRSQHQPAP 549
            |||:..:::||       ||.|:|.::.|| .:.|..:.|:..||.|||.|::|   ::...|||
 Frog   507 FKEVEGQSSNP-------VRAFSRVFIAVPGSDGGLLLVNDEQFIRNATTEEIR---KAFATPAP 561

  Fly   550 GAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGA 614
              .||:|                          ||.:|                       ||..
 Frog   562 --TPSSS--------------------------PVPVL-----------------------APVP 575

  Fly   615 QDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK 672
            .|      |::|....|.||..||:||||:..|||:.|..:|.||..|.|||..||||
 Frog   576 HD------MVQAFIQVSGMNAEWSQKCLEDNGWDFDQAGQIFMKLNAEGKIPDVAFMK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbr	NP_524660.1	Tap-RNA_bind	113..191	CDD:462696	22/78 (28%)
		leucine-rich repeat	215..255	CDD:275382	14/41 (34%)
		LRR	<252..>315	CDD:443914	19/62 (31%)
		leucine-rich repeat	256..281	CDD:275382	3/24 (13%)
		leucine-rich repeat	282..305	CDD:275382	8/22 (36%)
		leucine-rich repeat	306..336	CDD:275382	11/29 (38%)
		NTF2	372..531	CDD:238403	60/163 (37%)
		flgK	<548..>613	CDD:235895	9/64 (14%)
		TAP_C	609..671	CDD:197882	26/61 (43%)
nxf1	XP_031756030.1	Tap-RNA_bind	126..204	CDD:462696	22/79 (28%)
		leucine-rich repeat	231..273	CDD:275382	14/41 (34%)
		LRR	<270..>334	CDD:443914	20/63 (32%)
		leucine-rich repeat	274..299	CDD:275382	3/24 (13%)
		leucine-rich repeat	300..323	CDD:275382	8/22 (36%)
		leucine-rich repeat	324..354	CDD:275382	11/29 (38%)
		NTF2_like	389..540	CDD:471850	57/158 (36%)
		TAP_C	564..626	CDD:197882	31/116 (27%)