Protein Alignment sbr and nxf1b

DIOPT Version :10

• Sequence 1: NP_524660.1
• Gene: sbr / 43944
• FlyBaseID: FBgn0003321
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_001923961.2
• Gene: nxf1b / 323865
• ZFINID: ZDB-GENE-030131-2585
• Length: 645
• Species: Danio rerio
• Alignment Length: 688
• Identity: 223/688 - (32%)
• Similarity: 336/688 - (48%)
• Gaps: 102/688 - (14%)

  Fly     2 PKRGGGSSQRYNNNVGNGGGRYNAPED---FDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIK 63
            |:..||.|   ....|.|||....|..   .||.||......:|.::||  :.|.....|::|.:
Zfish    43 PRHRGGHS---GGGGGGGGGGGPGPRSRLHDDDGDVTMSDIPQDSSQRR--YNPYGRQQNRRDDR 102

  Fly    64 LRPEDLRRWDEDDDMSDMTTAVKDRPTSR---RRGSPIPRGKFGKLMPNSFGWYQVTLQNAQIYE 125
            .|.........|           ||..:|   |.|.....|..|.....|..|:::|:...:.|:
Zfish   103 NRKGGRGGGGND-----------DRGGNRFGGRGGGGGGGGGGGLSDGRSKNWFKMTIPYGKKYD 156

  Fly   126 KETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGI 190
            |:.|||: |.::.|..|....:.::.|...|:.:|...|..|..:.:.....|||::...:.|..
Zfish   157 KDWLLSS-LQSVCPIPFHAVQYHLDGNRAQFYVEDSTTANAIFKVSRRITDKDGYKVAVIMNSCP 220

  Fly   191 PLVAIDDAFK----EKMKVTMAKRYNIQTKALDLSRFHADPDL--KQVFCPLFRQNVMGAAIDIM 249
            |...|....|    |.:|..||||::...:||||:....||||  :.:...|.|:|.|.|.|.|:
Zfish   221 PPTLIHSDLKPADLEHLKQCMAKRFDGSQQALDLNNIRVDPDLVSQNIEVTLNRKNSMCAVIKII 285

  Fly   250 CDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNN 314
            .:|||:|..|||::|.:..::....:..::||||||.|..|::.:...|..|:.|.:::|.|:.|
Zfish   286 EENIPELVCLNLSNNRLFRLDDLVDIIHKVPNLKILNLSHNELKTERELDKLKGLKLVDLSLEGN 350

  Fly   315 PCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSE-QGRLLETKASYLCDVAGAEVVRQ 378
            |....:|....:||.:|.:||||:||||..|.|.|.|||.: ...|..:||||.|......::..
Zfish   351 PLCHHFKIHADYISAIRERFPKLLKLDGHDLPPPIGFDLDDGPSTLPPSKASYFCSEEIKNIILC 415

  Fly   379 FLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSAS---QAGRLNSFWKFNRNLRRLLNGEENRTR 440
            ||.|::.|:||||||.||||||:.|..|:|:|..|   ....|..:.|.:||::| :.....|.|
Zfish   416 FLQQFYNIYDSGNRQPLLDAYHDGATFSLSIPFVSLNPSKSTLGEYQKDSRNIKR-MKDPTTRYR 479

  Fly   441 NLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVR 505
            .:|:.||..|:.|:|.||||||..:|.||:..|..:::.|||.|:|||::.:     |.|.|  |
Zfish   480 LIKHTRLNVVAFLNELPKTQHDIASFVVDVNTYTATLLAFTVCGVFKEMDGK-----SRETY--R 537

  Fly   506 HFARTYVVVPQ-NNGFCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAG 569
            .|:|.::.||. :.|.||.|:.:|:.|||.|::|   |:...|||  .||:|
Zfish   538 AFSRVFIAVPAGSTGLCIVNDELFVRNATTEEIR---RAFVAPAP--TPSSS------------- 584

  Fly   570 LQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMN 634
                         ||..||                             :.:.:|:.|.|.:|.||
Zfish   585 -------------PVPTLS-----------------------------AHQQEMLAAFSLKSGMN 607

  Fly   635 VIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK 672
            :.||:|||::.:|||..||.:|..|..:.|||..||:|
Zfish   608 LEWSQKCLQDNDWDFERAAQIFTGLKAQGKIPDVAFVK 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbr	NP_524660.1	Tap-RNA_bind	113..191	CDD:462696	19/77 (25%)
		leucine-rich repeat	215..255	CDD:275382	17/41 (41%)
		LRR	<252..>315	CDD:443914	21/62 (34%)
		leucine-rich repeat	256..281	CDD:275382	5/24 (21%)
		leucine-rich repeat	282..305	CDD:275382	8/22 (36%)
		leucine-rich repeat	306..336	CDD:275382	9/29 (31%)
		NTF2	372..531	CDD:238403	64/162 (40%)
		flgK	<548..>613	CDD:235895	9/64 (14%)
		TAP_C	609..671	CDD:197882	22/61 (36%)
nxf1b	XP_001923961.2	None