Protein Alignment sbr and Nxf3

DIOPT Version :10

• Sequence 1: NP_524660.1
• Gene: sbr / 43944
• FlyBaseID: FBgn0003321
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_030107204.1
• Gene: Nxf3 / 245610
• MGIID: 2685230
• Length: 567
• Species: Mus musculus
• Alignment Length: 636
• Identity: 143/636 - (22%)
• Similarity: 248/636 - (38%)
• Gaps: 178/636 - (27%)

  Fly    69 LRRWDEDDDMSDMTTAVKDRPTSRRRGSPIPRGKF--GKLMPNSFGWYQVTLQNAQIYEKETLLS 131
            :::|::.|             .:...||..|..|.  .|....|..|::||:.....|:|:.||:
Mouse    69 VQKWNQTD-------------VNMEGGSKPPERKMQRDKQDDTSENWFKVTIPFGIKYDKKWLLN 120

  Fly   132 ALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLV--- 193
             |:.:.....|.|..:..|:....||.|:...|..::.:..        :::....:.|.:.
Mouse   121 -LIQSQCSIPFTPVQFHYEKMQAHFFVDNPNIAFMLKAISD--------KILDETDNKISIFISP 176

  Fly   194 -----AIDDAFKEKMKVTMA---KRYNIQTKALDLSRFHADPDL--KQVFCPLFRQNVMGAAIDI 248
                 ::.:...|||..||.   ::.....:.|:..|...|.||  :.....|..:..|..::.|
Mouse   177 CDEPHSVTELKLEKMDHTMLTTNQQCATSQRVLNRQRLPFDQDLMTRPTDLALVPRRYMTPSLSI 241

  Fly   249 MCDNI--------------PDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLV 299
            ..:::              ||||.:..:.:|:|:.     :..:..|:.
Mouse   242 HKEDMTQVNSEGEVAKVHAPDLEKICADQSSLSTT-----MPDKSSNIN---------------- 285

  Fly   300 VLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKA 364
                 |||||                        ||||:.|||:...........:...|...|.
Mouse   286 -----SILEL------------------------FPKLLSLDGQESHKPTLCGPEDHKTLSACKE 321

  Fly   365 SYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSASQAGRLNS---FWKFNR 426
            .:....:...:|.|||.||:.|:|:|:||.||:|||.:|..::::|.:|....:||   ::||:|
Mouse   322 IFFGSESIKTMVLQFLKQYYFIYDNGDRQGLLNAYHPEACFTLTIPFSSIDLSMNSLCEYFKFSR 386

  Fly   427 NLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELND 491
            |: ::|.....|.:.||:.:...:..|...||||||..:|.||:.:....|:.|:|:|||||:::
Mouse   387 NM-KILKDPYMRRQLLKHKKCDIIHFLRTLPKTQHDLTSFVVDICLQTEKMLCFSVSGLFKEVDN 450

  Fly   492 ETNNPASMELYDVRHFARTYVVVPQNNG-FCIRNETIFITNATHEQVREFKRSQHQPAPGAMPST 555
            ....       .:..|.|.:||...|:. .||.|:.:.:|| .||                :||.
Mouse   451 SAQG-------CMHAFTRIFVVTHDNSSELCIINDKLSVTN-VHE----------------VPSA 491

  Fly   556 SSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPG-AQDEST 619
            |:.|                                            |.|:|:..|. :||:
Mouse   492 STPV--------------------------------------------ATSSTSYLPSFSQDQ-- 510

  Fly   620 KMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAF 670
             .:|:....|||.:||..|:|.|.:..|::|.|......|..|:.|..:.|
Mouse   511 -QEMVPTFCAQSGVNVDRSQKSLHDDQWNYNRAIQSLALLKVEDTISEDKF 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbr	NP_524660.1	Tap-RNA_bind	113..191	CDD:462696	15/77 (19%)
		leucine-rich repeat	215..255	CDD:275382	8/55 (15%)
		LRR	<252..>315	CDD:443914	12/76 (16%)
		leucine-rich repeat	256..281	CDD:275382	4/24 (17%)
		leucine-rich repeat	282..305	CDD:275382	0/22 (0%)
		leucine-rich repeat	306..336	CDD:275382	5/29 (17%)
		NTF2	372..531	CDD:238403	55/162 (34%)
		flgK	<548..>613	CDD:235895	7/64 (11%)
		TAP_C	609..671	CDD:197882	19/63 (30%)
Nxf3	XP_030107204.1	Tap-RNA_bind	102..181	CDD:462696	16/87 (18%)
		NTF2_like	328..484	CDD:471850	55/163 (34%)
		TAP_C	499..561	CDD:197882	20/65 (31%)