DRSC/TRiP Functional Genomics Resources

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Protein Alignment sbr and nxf-2

DIOPT Version :9

Sequence 1:NP_524660.1 Gene:sbr / 43944 FlyBaseID:FBgn0003321 Length:672 Species:Drosophila melanogaster
Sequence 2:NP_506568.2 Gene:nxf-2 / 179938 WormBaseID:WBGene00003835 Length:405 Species:Caenorhabditis elegans


Alignment Length:348 Identity:79/348 - (22%)
Similarity:156/348 - (44%) Gaps:35/348 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   218 LDLSRFHADPDLKQ---VFCPLFRQNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRL 279
            |:||.|..:.:..:   :.| |.:..||...:..:....|.:..::.::|.:..::....:....
 Worm    58 LNLSNFSKNTEFVERDMLMC-LTKTRVMSVVLQHIGYKYPRISGISFSNNRLCHLDHLSSLSSIS 121

  Fly   280 PNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGET 344
            ..||.|.|..|:|.|...|..|..:.:..:..:.||...::....::.:.:::.|||...|||..
 Worm   122 KFLKFLDLSHNQISSGEELKKLGTIPVETVFFEGNPVCEKFVQCAEYANFIQKTFPKCSNLDGME 186

  Fly   345 LEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGN----RQALLDAY------ 399
            :||:...:..||  ::..:..|........:|.:|:..|::|:|..:    |:.|||||      
 Worm   187 VEPKPDHNRIEQ--IIPFRNGYYGSDEVRTLVEEFIITYYKIYDGADGQQTRKQLLDAYDTNNST 249

  Fly   400 --HEKAML-----SISMPSASQAGRLNSFWKFNRNLRRLLNGE---ENRTRNLKYGRLACVSTLD 454
              |....|     .:..|.:      .|:..:.|....:||.|   .||...:.:|.:..|..|.
 Worm   250 FTHTVVCLWDPIKFVMYPDS------ESYRMYLRTSHNVLNQEYFAANRASRISHGAMDIVVALS 308

  Fly   455 EWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNG 519
            ..|.|.|...||.||:.:.:.:::.||:.|.|:: ......|.:.|.:| .:|.||::|.|:..|
 Worm   309 RLPATIHLMDTFVVDVFLVSATLLGFTLHGTFRD-GPSAIKPENTEEHD-NYFTRTFMVAPRGEG 371

  Fly   520 -FCIRNETIFITNATHEQVREFK 541
             ..|.::.:||::.:..:..:::
 Worm   372 KVAIVSDQLFISSMSKRRGDQYR 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sbrNP_524660.1 Tap-RNA_bind 112..191 CDD:286271
leucine-rich repeat 215..255 CDD:275382 8/39 (21%)
LRR_RI <223..341 CDD:238064 21/120 (18%)
LRR_8 256..315 CDD:290566 10/58 (17%)
LRR_4 256..298 CDD:289563 8/41 (20%)
leucine-rich repeat 256..281 CDD:275382 1/24 (4%)
leucine-rich repeat 282..305 CDD:275382 9/22 (41%)
leucine-rich repeat 306..336 CDD:275382 3/29 (10%)
NTF2 372..531 CDD:238403 47/179 (26%)
Big_3_5 <578..>614 CDD:293246
TAP_C 609..671 CDD:197882
nxf-2NP_506568.2 leucine-rich repeat 55..97 CDD:275382 8/39 (21%)
leucine-rich repeat 98..123 CDD:275382 1/24 (4%)
leucine-rich repeat 124..147 CDD:275382 9/22 (41%)
leucine-rich repeat 148..178 CDD:275382 3/29 (10%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3763
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H38176
Inparanoid 1 1.050 117 1.000 Inparanoid score I3370
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1051093at2759
OrthoFinder 1 1.000 - - FOG0000862
OrthoInspector 1 1.000 - - otm14803
orthoMCL 1 0.900 - - OOG6_102057
Panther 1 1.100 - - LDO PTHR10662
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R710
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1110.900

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