DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment or and AP1S3

DIOPT Version :9

Sequence 1:	NP_536793.1	Gene:	or / 43943	FlyBaseID:	FBgn0003008	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_001034658.1	Gene:	AP1S3 / 130340	HGNCID:	18971	Length:	154	Species:	Homo sapiens

Alignment Length:	147	Identity:	50/147 - (34%)
Similarity:	88/147 - (59%)	Gaps:	6/147 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKAILVFNNHGKPRLSKFYQYFDESLQQQIIKETFQLVSKRDDNVCNFLEGGSLIGGSDYKLIY 65
            ||..||:|:..||.||.|:|....:..:::|.:|..|::..|.....:|::...|      ||:|
Human     1 MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKEL------KLVY 59

  Fly    66 RHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHADAVHHILSELVMGGMVL 130
            :.||:|||...:::.::||..|:::..:||.|||.|.||||||:||:.:..:.||.|.::||.:.
Human    60 KRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQ 124

  Fly   131 QTNMNDIMARIEEQNKI 147
            :|:....:..||:.:.:
Human   125 ETSKKIAVKAIEDSDML 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
or	NP_536793.1	AP3_sigma	1..146	CDD:341438	50/144 (35%)
AP1S3	NP_001034658.1	AP1_sigma	3..143	CDD:341435	48/145 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53551
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820