Protein Alignment Men-b and me2

DIOPT Version :10

• Sequence 1: NP_001163750.1
• Gene: Men-b / 43936
• FlyBaseID: FBgn0029155
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_001003627.2
• Gene: me2 / 445233
• ZFINID: ZDB-GENE-040801-147
• Length: 581
• Species: Danio rerio
• Alignment Length: 562
• Identity: 303/562 - (53%)
• Similarity: 398/562 - (70%)
• Gaps: 10/562 - (1%)

  Fly    47 CPSQVRGIDHIRD--------PRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRY 103
            |.|..|.: |.::        ||.|||:||||:|||.||||||.|::.:||:.|....:..:.:.
Zfish    12 CVSMCRWV-HTKEKGKPLMLNPRTNKGMAFTLKERQMLGIHGLLPSKIETQDTQAMRFQKNLKKM 75

  Fly   104 TEPLNKYLYLSDLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDR 168
            ::||.||:||..:.:||||||:|.|.|:||.||||||||||||||.::|.|:|||.||||:..|:
Zfish    76 SDPLQKYIYLMGIQERNERLFYRVLMEDIEALMPIVYTPTVGLACTQYGHIFRRPKGLFISIKDQ 140

  Fly   169 GHIFDVMKNWPEPNVRAICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDV 233
            |||..::.|||:.:|:|:.||||||||||||||..|||||||||.||||.|||:|..|||:.:||
Zfish   141 GHIRSILDNWPDTSVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPESCLPVCIDV 205

  Fly   234 GTNNIDLLEDPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYR 298
            ||:|..||.||.|:||.|:|...:.||:.|||||||||.:|||:|||||||||||||||||.|||
Zfish   206 GTDNEKLLRDPFYMGLYQRRDRSQRYDDLIDEFMEAVVDKYGQDTLIQFEDFGNHNAFRFLKKYR 270

  Fly   299 NTYCTFNDDIQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIE 363
            ..|||||||||||||||:|||.|::|..||...::..||.||||||:|||:|.|.||::.|:...
Zfish   271 EKYCTFNDDIQGTASVALAGLLAAQRAVGKPLTEHKVLFLGAGEAALGIANLIVMAMMESGMSQA 335

  Fly   364 EAYNRIYMVDIDGLLTKSRKVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTP 428
            :|..:|:|.|..|||.|.|........:.....|...:....:.|:.|||:.:||.|.|..:||.
Zfish   336 DARKKIWMFDKYGLLVKDRAYETDSNQEAFVHPDPGDVKSFLDAVNVIKPTAIIGVSGAGRLFTH 400

  Fly   429 EILRTMADNNERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGD-KTFYPGQGN 492
            ::::.|.:.||||::|||||||:||||||||||..|..|.:|:|||||.||.:.| :...|||||
Zfish   401 DVIKAMGNLNERPIIFALSNPTAKAECTAEDAYSLTQGRCLFASGSPFAPVSLEDGRILTPGQGN 465

  Fly   493 NAYIFPGVGLGVICTGTHHIPDEMFLIAAQELANFVEPSDIERGSLYPPLSSIRNVSMNIAVGVT 557
            ||||||||.|.||.:|..||.|.:||.||:.||:.:...::.:|.||||||:||.||:.:|:.|.
Zfish   466 NAYIFPGVALAVILSGVRHISDTVFLEAAKTLADQLTDEELSQGRLYPPLSNIREVSLQMAIKVV 530

  Fly   558 KCAYDRGLASTYPEPQDKRKWLENQLYNFNYESSMPASWVWP 599
            :..|.:|:|..||||.||..::.:.::|.||:|.:|..:.||
Zfish   531 EYVYSKGMAFRYPEPVDKESYVRSVVWNTNYDSFLPDIYDWP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men-b	NP_001163750.1	PLN03129	51..590	CDD:215594	297/547 (54%)
me2	NP_001003627.2	PLN03129	18..565	CDD:215594	297/547 (54%)