Protein Alignment Men-b and Menl-2

DIOPT Version :10

• Sequence 1: NP_001163750.1
• Gene: Men-b / 43936
• FlyBaseID: FBgn0029155
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 573
• Identity: 256/573 - (44%)
• Similarity: 366/573 - (63%)
• Gaps: 21/573 - (3%)

  Fly    57 IRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLSDLYDRNE 121
            :.:.:.|||||||::|||.|||.||.|...::.::|:.............:.::.|||.::.|:.
  Fly    42 VMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHR 106

  Fly   122 RLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDRGHIFDVMKNWPEPNVRAI 186
            ||::||:.||||..:|||||||||.....:||.:::...|||:.:|:|||.|:|.||.:..|:||
  Fly   107 RLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAI 171

  Fly   187 CVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLEDPLYVGLRQ 251
            |||||.|:|||||:||..|||.:||:.|||||..|.|...:|:.:||||:|..||:||||||.|.
  Fly   172 CVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARI 236

  Fly   252 KRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAV 316
            .||.|.||||.:|||||:.|:.:|.||.|.||||...||.:||:||:..||.||||||||.:..:
  Fly   237 PRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGL 301

  Fly   317 AGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMVDIDGLLTKS 381
            |.....:||||:..:|..|||.|||.||:|||::....:...|:|.|||...||::|::|:||..
  Fly   302 AAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGILTPE 366

  Fly   382 R----KVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADNNERPV 442
            .    ::|.:      :.|.:.||.|:..::..:|||||:||:...|||..|:|:|||.|:|||.
  Fly   367 SPNPPEMGKI------FIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPA 425

  Fly   443 VFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGDKTFYPGQGNNAYIFPGVGLGVICT 507
            ||.|||||:.:|||||.|:.||:.||:|.||||||||.|..|.:.|.|.||...|||:.|..|..
  Fly   426 VFPLSNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITA 490

  Fly   508 GTHHIPDEMFLIAAQELANFVEPSDIERGSLYPPLSSIRNVSMNIAVGVTKCAYDRGLASTYPEP 572
            ...::|:|:|.:.:.|||.......::.|:|:||:....||:.|:.|.:|:...|..|::.||:|
  Fly   491 KARYLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKP 555

  Fly   573 QDKRKWLENQLYNFNYESSMPASWVWPRMPYIKTRDLVPT---KLYGKQKSEE 622
            .|..::::..||.|:|.:|:|.:|.:|..|        ||   |...|.|.:|
  Fly   556 DDICEFVKRSLYKFDYRNSLPTTWDYPVEP--------PTPKPKTKPKTKPKE 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men-b	NP_001163750.1	PLN03129	51..590	CDD:215594	245/536 (46%)
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	245/536 (46%)