Protein Alignment Men-b and men-1

DIOPT Version :10

• Sequence 1: NP_001163750.1
• Gene: Men-b / 43936
• FlyBaseID: FBgn0029155
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_496968.1
• Gene: men-1 / 175079
• WormBaseID: WBGene00012983
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 296/553 - (53%)
• Similarity: 387/553 - (69%)
• Gaps: 4/553 - (0%)

  Fly    50 QVRGIDHIRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLS 114
            |.||||.::.|.||||:||:|.|||.||:|||.|..|.|:|:|.......:.:..:.|.||:.|.
 Worm    48 QKRGIDLLKSPGLNKGMAFSLHERQYLGVHGLLPPAFMTEEQQAYRIITKLRQQPDNLAKYIQLD 112

  Fly   115 DLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDR--GHIFDVMKN 177
            .|.||||:|::|.|.:|:::|||||||||||.|||.||.|||.|.||:||.||.  ..|..::.|
 Worm   113 SLQDRNEKLYYRVLCDNVKELMPIVYTPTVGQACQHFGFIYRNPKGLYITINDNSISKIHQILAN 177

  Fly   178 WPEPNVRAICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLE 242
            ||..|||||.:|||||||||||||..|:||||||||||.|||||:|..|||:::||||:|.:||.
 Worm   178 WPTENVRAIVITDGERILGLGDLGTYGIGIPVGKLALYVALAGIRPEWCLPVILDVGTDNSELLN 242

  Fly   243 DPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDD 307
            ||.|.|||:|||.|.|||..:|.||:|..:|:|::||||||||||.||:|.||:|:..||.||||
 Worm   243 DPFYTGLRRKRVRGPEYDTLVDNFMKAATKRFGRDTLIQFEDFGNQNAYRLLDRYKGEYCMFNDD 307

  Fly   308 IQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMV 372
            |||||:|.||||.||.|||.|.......:|.|||.||.|:|::.|:.|:.:|:..|||..|||||
 Worm   308 IQGTAAVVVAGLLASTRITKKKLSQERIVFLGAGGAATGVAEMCVRQMMDEGLSEEEACGRIYMV 372

  Fly   373 DIDGLLTKSRKVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADN 437
            ||:||:|.||. .:|....:.:|||:....:|.|:|.|:||..|||||..||.||.:|::.||..
 Worm   373 DIEGLITTSRS-KSLGERHVKFAKDLPDTKNLLEVVKTVKPGALIGASTVAGAFTEDIIKEMARL 436

  Fly   438 NERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGDKTFYPGQGNNAYIFPGVGL 502
            |.||::|||||||||||||||.||:.|:..|:|:|||||..|::..|.:.|||||||||||||.|
 Worm   437 NPRPIIFALSNPTSKAECTAETAYRCTNGAVLFASGSPFENVEMNGKLYKPGQGNNAYIFPGVAL 501

  Fly   503 GVICTGTHHIPDEMFLIAAQELANFVEPSDIERGS-LYPPLSSIRNVSMNIAVGVTKCAYDRGLA 566
            |.:...|.:|||::||:||:.:|..|....:...| :||.|..||.:|:.|||.|.:..|...||
 Worm   502 GAVLFRTKNIPDKLFLLAARMVAEAVSEKSLNTYSRVYPRLKDIRELSVKIAVEVGEYCYRHDLA 566

  Fly   567 STYPEPQDKRKWLENQLYNFNYESSMPASWVWP 599
            :.:|:|.|...::...||:..|:..:..::.||
 Worm   567 TLHPKPDDMEMFIRQNLYSVEYDELINKTYEWP 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men-b	NP_001163750.1	PLN03129	51..590	CDD:215594	293/541 (54%)
men-1	NP_496968.1	PLN03129	46..592	CDD:215594	294/544 (54%)