Protein Alignment Men-b and me1

DIOPT Version :9

• Sequence 1: NP_001163750.1
• Gene: Men-b / 43936
• FlyBaseID: FBgn0029155
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: XP_002938500.1
• Gene: me1 / 100489590
• XenbaseID: XB-GENE-1013221
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 567
• Identity: 315/567 - (55%)
• Similarity: 406/567 - (71%)
• Gaps: 17/567 - (2%)

  Fly    37 HYHEVVGDIICPSQVRGIDHIRDPRLNKGLAFTLEERQTLGIHGLQPARFKTQEEQLQLCKIAVN 101
            ||          ::.||.|..|||.||||:||:||||..||||||.|..|.:|:  :|:.::..|
 Frog    27 HY----------TKKRGYDITRDPHLNKGMAFSLEERLQLGIHGLLPPCFLSQD--VQVLRVLRN 79

  Fly   102 --RYTEPLNKYLYLSDLYDRNERLFFRFLSENIEDLMPIVYTPTVGLACQRFGLIYRRPHGLFIT 164
              |....|::|:.|..|.||||:||::.|:.:||..||:|||||||||||::||.:|||.|||||
 Frog    80 YERQKCDLDRYILLMGLQDRNEKLFYKVLTSDIERFMPVVYTPTVGLACQQYGLAFRRPRGLFIT 144

  Fly   165 YNDRGHIFDVMKNWPEPNVRAICVTDGERILGLGDLGACGMGIPVGKLALYTALAGIKPHQCLPI 229
            .:|||||..|||:|||.|::|:.||||||||||||||:.||||||||||||||..|::|.:|||:
 Frog   145 IHDRGHISTVMKSWPEDNIKAVVVTDGERILGLGDLGSYGMGIPVGKLALYTACGGVQPQECLPV 209

  Fly   230 VVDVGTNNIDLLEDPLYVGLRQKRVVGREYDEFIDEFMEAVVQRYGQNTLIQFEDFGNHNAFRFL 294
            ::||||:|.:||.||||:|||.:||.|:||||.:||||:||.:|||.|.|||||||.|.||||.|
 Frog   210 MLDVGTDNQELLNDPLYIGLRHRRVRGKEYDELVDEFMKAVTERYGINCLIQFEDFANANAFRLL 274

  Fly   295 DKYRNTYCTFNDDIQGTASVAVAGLYASKRITGKSFKDYTFLFAGAGEAAIGIADLTVKAMVQDG 359
            :.|||.||||||||||||:||||||..:.|||.....|:|.||.||||||:|||||.|.||.::|
 Frog   275 NMYRNKYCTFNDDIQGTAAVAVAGLLGALRITKNKLSDHTVLFQGAGEAAMGIADLIVMAMEKEG 339

  Fly   360 VPIEEAYNRIYMVDIDGLLTKSRKVGNLDGHKIHYAKDINPMSDLAEIVSTIKPSVLIGASAAAG 424
            .|.:.|...|:|||..||:.|.|  .:|:..|..:|.....|..|.|:|..|||:||||.:|..|
 Frog   340 TPRDAAIKNIWMVDSKGLIVKGR--ASLNHEKERFAHPHKEMKSLEEVVKDIKPTVLIGVAAIGG 402

  Fly   425 IFTPEILRTMADNNERPVVFALSNPTSKAECTAEDAYKHTDARVIFSSGSPFPPVQIGD-KTFYP 488
            .||.:|::.||..|.||::|||||||||||||||..|:.|..|.||:|||||.||.:.| :|.||
 Frog   403 AFTEQIIKDMASFNNRPIIFALSNPTSKAECTAEQCYRLTQGRGIFASGSPFDPVTLPDGRTLYP 467

  Fly   489 GQGNNAYIFPGVGLGVICTGTHHIPDEMFLIAAQELANFVEPSDIERGSLYPPLSSIRNVSMNIA 553
            |||||||:||||.|||:..|..||.|::||..|:.:|..|....:|.|.|||||.:|:.||:.||
 Frog   468 GQGNNAYVFPGVALGVVACGVRHISDDVFLTTAEIIAQQVSDKHLEEGRLYPPLQTIQEVSVKIA 532

  Fly   554 VGVTKCAYDRGLASTYPEPQDKRKWLENQLYNFNYESSMPASWVWPR 600
            |.:.:.||....||.:|||::|..::.:|:|:.:|:..|..|:.||:
 Frog   533 VKIVENAYKDNSASVFPEPENKEAFVRSQMYSTDYDQFMVDSYSWPQ 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men-b	NP_001163750.1	PLN03129	51..590	CDD:215594	309/541 (57%)
		malic	117..298	CDD:278802	122/180 (68%)
		NAD_bind_1_malic_enz	308..585	CDD:133454	143/277 (52%)
me1	XP_002938500.1	PLN03129	31..571	CDD:215594	309/543 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	273	1.000	Domainoid score	I1752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	630	1.000	Inparanoid score	I836
OMA	1	1.010	-	-		QHG60768
OrthoDB	1	1.010	-	-		D334471at33208
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm9538
Panther	1	1.100	-	-	LDO	PTHR23406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080