Protein Alignment Men-b and me3

DIOPT Version :9

• Sequence 1: NP_001163750.1
• Gene: Men-b / 43936
• FlyBaseID: FBgn0029155
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: XP_031751513.1
• Gene: me3 / 100135099
• XenbaseID: XB-GENE-973120
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 321/596 - (53%)
• Similarity: 413/596 - (69%)
• Gaps: 8/596 - (1%)

  Fly    10 TVGKLCRCGTSATGKTA-VAAATVPTARHYHEVV--GDIICPSQV--RGIDHIRDPRLNKGLAFT 69
            :||.....|.:..|..| |.:...|:.|..|...  |..:.|..:  ||.|..|:|.||||:|||
 Frog    22 SVGLRAASGAARLGLWAPVLSHAQPSIRVCHTAAGGGTPVKPQAIKKRGYDITRNPYLNKGMAFT 86

  Fly    70 LEERQTLGIHGLQPARFKTQEEQLQLCKIAVNRYTEPLNKYLYLSDLYDRNERLFFRFLSENIED 134
            ||||..||||||.|..|.:|:.|:.....:....:..|:||:.|..|.||||:||:|.|:.:||.
 Frog    87 LEERLQLGIHGLLPPCFLSQDVQVLRVMKSYETKSSDLDKYIILMTLQDRNEKLFYRVLTSDIER 151

  Fly   135 LMPIVYTPTVGLACQRFGLIYRRPHGLFITYNDRGHIFDVMKNWPEPNVRAICVTDGERILGLGD 199
            .||||||||||||||::||.:|||.|||||.:|:|||..::.:|||.:::||.||||||||||||
 Frog   152 FMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDKGHIATMLNSWPEEDIKAIVVTDGERILGLGD 216

  Fly   200 LGACGMGIPVGKLALYTALAGIKPHQCLPIVVDVGTNNIDLLEDPLYVGLRQKRVVGREYDEFID 264
            ||..||||||||||||||..|:.|.||||:::||||:|..||.||||:||:.|||.|::|||.||
 Frog   217 LGGYGMGIPVGKLALYTACGGVHPQQCLPVLLDVGTDNEALLNDPLYIGLKHKRVRGKQYDELID 281

  Fly   265 EFMEAVVQRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAVAGLYASKRITGKS 329
            |||:||..:||.|.|||||||.|.||||.|:||||.||||||||||||||||||:.|:.|||...
 Frog   282 EFMQAVTNKYGMNCLIQFEDFANSNAFRLLNKYRNKYCTFNDDIQGTASVAVAGILAALRITNNR 346

  Fly   330 FKDYTFLFAGAGEAAIGIADLTVKAMVQDGVPIEEAYNRIYMVDIDGLLTKSRKVGNLDGHKIHY 394
            ..|:.|:|.||||||:|||.|...||.::|...|:|..:|:|||..||:.|.|  |||:..|..:
 Frog   347 LSDHKFVFQGAGEAAMGIAQLITMAMEKEGTSREDAIKKIWMVDSKGLIVKGR--GNLNHEKDVF 409

  Fly   395 AKDINPMSDLAEIVSTIKPSVLIGASAAAGIFTPEILRTMADNNERPVVFALSNPTSKAECTAED 459
            |.|...:..|.|.|..:||:.:||.:|..|.||.:|::.||..|:||::|||||||||||||||.
 Frog   410 AHDHPQVKTLEEAVQILKPTAIIGVAAIGGAFTEKIIKDMAAFNKRPIIFALSNPTSKAECTAEQ 474

  Fly   460 AYKHTDARVIFSSGSPFPPVQIGD-KTFYPGQGNNAYIFPGVGLGVICTGTHHIPDEMFLIAAQE 523
            .|:.|:.|.||:|||||..|.:.: :|||||||||||:||||.||||..|..||.:::||..|:.
 Frog   475 CYQLTEGRGIFASGSPFSKVTLANGQTFYPGQGNNAYVFPGVALGVIGCGVRHISEDLFLTTAET 539

  Fly   524 LANFVEPSDIERGSLYPPLSSIRNVSMNIAVGVTKCAYDRGLASTYPEPQDKRKWLENQLYNFNY 588
            :|..|...::..|.|||||||||:||..|||.:...||...:||.||||:||..::.:.:|:.:|
 Frog   540 IAEMVTAENLAEGRLYPPLSSIRDVSFKIAVKIVDYAYKNNMASWYPEPEDKESFVRSLIYSPDY 604

  Fly   589 ESSMPASWVWP 599
            :|....|:.||
 Frog   605 DSFTIDSYNWP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men-b	NP_001163750.1	PLN03129	51..590	CDD:215594	306/541 (57%)
		malic	117..298	CDD:278802	121/180 (67%)
		NAD_bind_1_malic_enz	308..585	CDD:133454	142/277 (51%)
me3	XP_031751513.1	PLN03129	29..608	CDD:215594	316/580 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	273	1.000	Domainoid score	I1752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H100773
Inparanoid	1	1.050	630	1.000	Inparanoid score	I836
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D334471at33208
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm9538
Panther	1	1.100	-	-	O	PTHR23406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160