Protein Alignment NtR and HTR3A

DIOPT Version :9

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_998786.3
• Gene: HTR3A / 3359
• HGNCID: 5297
• Length: 510
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 64/359 - (17%)
• Similarity: 126/359 - (35%)
• Gaps: 102/359 - (28%)

  Fly   248 LAYEQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQ 312
            |..::.:.:|.|.:....:|.|..|.|.||||.::.....|...||.|  ::|......:|:...
Human    71 LNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVP--DILINEFVDVGKSPN 133

  Fly   313 SYELMVYANGSITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPI 377
            ...:.:...|.:..| :.||:.:.|.....|:|.:...|.:
Human   134 IPYVYIRHQGEVQNY-KPLQVVTACSLDIYNFPFDVQNCSL------------------------ 173

  Fly   378 APNEHVNTPSGWSFTQMSVVL--------VEND-----SQRRYNPKGMMQKMTGDVAIEFTLQRN 429
                   |.:.|..|...:.:        |::|     :|..:...|::....     ||:::.:
Human   174 -------TFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFR-----EFSMESS 226

  Fly   430 RSFYMTVFYLPLIACQMFLILSFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYK 494
            ..:....||:.:....:|.::|.:|     .|:.|:.:.|..:            |:||......
Human   227 NYYAEMKFYVVIRRRPLFYVVSLLL-----PSIFLMVMDIVGF------------YLPPNSGERV 274

  Fly   495 VIMMTTTYCYILHICII------------WLDLYPPRSK-------APGWLVRVINSNVLRCILG 540
            ...:|....|.:.:.|:            .:...||.|:       ||..|:.|..::.|.| .|
Human   275 SFKITLLLGYSVFLIIVSDTLPATAIGTPLIGKAPPGSRAQSGEKPAPSHLLHVSLASALGC-TG 338

  Fly   541 LRFSDSTDYCDIQENPWHHMAKILNNLSSILVII 574
            :.|.    .|         ||.::.:|:..:.|:
Human   339 VYFV----VC---------MALLVISLAETIFIV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	34/193 (18%)
HTR3A	NP_998786.3	LIC	23..504	CDD:273305	64/359 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810