DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NtR and acr-17

DIOPT Version :9

Sequence 1:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001023961.1	Gene:	acr-17 / 191603	WormBaseID:	WBGene00000056	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	401	Identity:	85/401 - (21%)
Similarity:	160/401 - (39%)	Gaps:	81/401 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 FDGYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHM 263
            |..|..|:.| ||:|                :|.|.|: ::..:|:.....:| ...::.....:
Worm    32 FRDYHKELRP-VKDE----------------SSGPTNV-TVQLYFKQIQKVHE-NDQIITLYCWI 77

  Fly   264 MMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYA 328
            ..:|:|..|.|.|.|||:::|...|...||||.:.|.|.|..::.:......:.:...|.|:|:.
Worm    78 EEYWQDEFLTWNPSDFGNIKSLHVPSEMIWKPDLLVYNNANMNIKENEMQTNVQIEHTGKISLFR 142

  Fly   329 Q-------NLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPI-APNEHVNT 385
            .       :||:        ..:|.::..|.|.|.....:|.:   ::.:...:|. ||.:..||
Worm   143 AIITDITCDLQM--------EKFPYDQQICFIMLASWSYDGSQ---IMLNTAEQPTEAPLDIKNT 196

  Fly   386 PSGWSFTQMSVV--LVEN------DSQRRYNPK--GMMQKMTGDVAIEFTLQRNRSFYMTVFYLP 440
                  |.::::  .:.|      |.:.|.|.|  ........|::..|.::||.|:|:....:|
Worm   197 ------TNLAILNHYIPNMEWKLVDFRYRNNLKYYDCCPNPYPDISYFFAIKRNPSYYLFTLIIP 255

  Fly   441 LIACQMFLILSFVL------RSTRRSSLILIALLIAAWGLMYMT-RYASPHYVPPMMTAYKV--- 495
            .....:..::.|..      .:|.:.||.:.|||..|..||.:: :..:.....|::..|.:
Worm   256 SAFITIVTVIGFFTPHSSTGENTEKVSLGVTALLSLAIILMMVSDKLPATSNSVPLLGQYYIGLI 320

  Fly   496 -IMMTTTYCYILHICIIWLDLYPPRSKAPGWLVRVINSNVLRCILGLRFSDSTDYCDIQENPWHH 559
             ||...|||....:.|          :..|...|.|...:...:|.:|.:.::   .:|   |..
Worm   321 FIMFLATYCTTFTLGI----------QMQGNAGRPITRRLRSFLLSIRMNRNS---FVQ---WFF 369

  Fly   560 MAKILNNLSSI 570
            ..:::|...||
Worm   370 GRELMNTQESI 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	46/234 (20%)
acr-17	NP_001023961.1	LIC	23..491	CDD:273305	85/401 (21%)
		Neur_chan_LBD	24..245	CDD:280998	53/248 (21%)
		Neur_chan_memb	252..491	CDD:280999	29/145 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5703
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910