DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NtR and acr-7

DIOPT Version :9

Sequence 1:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_495647.1	Gene:	acr-7 / 174262	WormBaseID:	WBGene00000046	Length:	538	Species:	Caenorhabditis elegans

Alignment Length:	368	Identity:	68/368 - (18%)
Similarity:	129/368 - (35%)	Gaps:	81/368 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 GFDGYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFH-FQTRSLAYEQTSSLLQTRM 261
            ||...||:     ||......||::.:........|....:::.. |..:.|..:....:::...
Worm    22 GFTVEGSK-----KEAQLYRDLLTNYSYLVRPVRNPKKALTVTMKVFIQQVLLVDAKHQMIEVNA 81

  Fly   262 HMMMHWRDSRLVWKPEDFGSLES--FEHPDLRIWKPHMNVLNGAL---QSMGQVLQSYELMVYAN 321
            .:...|.|.||.|.|.|:.::.|  |:..| :||:|.:.:.|..:   |....:......:.|::
Worm    82 WLKYIWTDFRLRWNPLDYENITSVRFQGED-QIWQPDILLYNRYIEDEQESFDITYKTNAVAYSD 145

  Fly   322 G----------------SITLYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIY 370
            |                .|||:..:.|:   |.....:|.......|:.|.:  .:|||
Worm   146 GVINWIPPGIFKLSCKMDITLFPFDEQI---CFMKFGSWTYHGFALDLRLDV--VKGQE------ 199

  Fly   371 DDQRKPIAPNEHVNTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMT 435
                 |.|......|...|.       |:...::|........::....|.....|:|...:|:.
Worm   200 -----PSADLSTYITNGEWH-------LLSAPARREEKFYKCCKEPYPTVKFYLHLRRRTFYYVF 252

  Fly   436 VFYLPLIACQMFLILSFVLRSTRRS------SLILIALLIAAWGLMYMTR------------YAS 482
            ...||.:......:|:|.|.:|..|      :.||:::......|..||.            :::
Worm   253 NVVLPTLLVSFMSLLAFCLPATDLSEKIGLQTTILLSVCFFLTILSEMTPTTSEAVPLLGVFFSA 317

  Fly   483 PHYVPPMMTAYKVIMMTTTYCYILH------------ICIIWL 513
            ..::..|.|.:.::::...|..|.:            .|:.||
Worm   318 LTFIVAMSTTFTILVLNIRYRQITNHYLSPMFRSIFLECLPWL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	42/238 (18%)
acr-7	NP_495647.1	LIC	28..524	CDD:273305	65/362 (18%)
		Neur_chan_LBD	31..247	CDD:280998	43/239 (18%)
		Neur_chan_memb	254..524	CDD:280999	19/107 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910