Protein Alignment NtR and CHRNE

DIOPT Version :9

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_000071.1
• Gene: CHRNE / 1145
• HGNCID: 1966
• Length: 493
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 72/373 - (19%)
• Similarity: 145/373 - (38%)
• Gaps: 56/373 - (15%)

  Fly   187 GSNTARWFYDCGFDGYGSEIAPIVK-EETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAY 250
            |.|.....|...|:.|.....|:.: |:|.|             .|:...|:::        ::.
Human    20 GKNEELRLYHHLFNNYDPGSRPVREPEDTVT-------------ISLKVTLTNL--------ISL 63

  Fly   251 EQTSSLLQTRMHMMMHWRDSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYE 315
            .:....|.|.:.:.:.|:|.||.:..:|||.:|:...|...:|.|.: ||...:.....|.....
Human    64 NEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEI-VLENNIDGQFGVAYDAN 127

  Fly   316 LMVYANGSIT-----LYAQNLQLASWCVDSARNWPSERVTCDI---ELGLNGQEGQENVALIYDD 372
            ::||..||:|     :|      .|.|......:|.:...|.:   ....|.:|.:...|:  |:
Human   128 VLVYEGGSVTWLPPAIY------RSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTFAV--DN 184

  Fly   373 QRKPIAP---NEHVNTPSG-WSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFY 433
            ..|.|..   :....|.:| |:......|:      ||::..........||.....::|...||
Human   185 DGKTINKIDIDTEAYTENGEWAIDFCPGVI------RRHHGGATDGPGETDVIYSLIIRRKPLFY 243

  Fly   434 MTVFYLPLIACQMFLILSFVL--RSTRRSSLILIALLIAAWGLMYMTRYASPH--YVPPMMTAYK 494
            :....:|.:.....::|::.|  ::..:...:.|.:|:|....:::.....|.  ...|::..:.
Human   244 VINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRFL 308

  Fly   495 VIMMTTTYCYILHICIIWLDL--YPPRSKAPGWLVRVINSNVLRCILG 540
            :.:|......::: |:|.|::  ..|.:.|....:|.:...:|..:||
Human   309 IFVMVVATLIVMN-CVIVLNVSQRTPTTHAMSPRLRHVLLELLPRLLG 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052	2/3 (67%)
		Neur_chan_LBD	212..429	CDD:280998	45/228 (20%)
CHRNE	NP_000071.1	LIC	21..475	CDD:273305	71/372 (19%)
		Neur_chan_LBD	24..240	CDD:280998	50/251 (20%)
		Neur_chan_memb	247..474	CDD:280999	18/110 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910