Protein Alignment NtR and Chrna4

DIOPT Version :9

• Sequence 1: NP_651958.2
• Gene: NtR / 43935
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_056545.3
• Gene: Chrna4 / 11438
• MGIID: 87888
• Length: 629
• Species: Mus musculus
• Alignment Length: 365
• Identity: 78/365 - (21%)
• Similarity: 146/365 - (40%)
• Gaps: 32/365 - (8%)

  Fly   213 ETKT---EKLLSHLNIQAENASMP-ANLSSISFHFQTRSLA----YEQTSSLLQTRMHMMMHWRD 269
            ||:.   |:||..|.......|.| ||:|.:.......|:|    .::.:.::.|.:.:...|.|
Mouse    33 ETRAHAEERLLKRLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHD 97

  Fly   270 SRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQLA 334
            .:|.|.|.|:.::.|...|...||:|.:.:.|.|..... |....:..::.:|.:......:..:
Mouse    98 YKLRWDPGDYENVTSIRIPSELIWRPDIVLYNNADGDFA-VTHLTKAHLFYDGRVQWTPPAIYKS 161

  Fly   335 SWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQR-KPIAPNEHVNTPSGWSFTQMSVVL 398
            |..:| ...:|.::..|.::.|          :..||..: ..::.:..|:....|...:..:|
Mouse   162 SCSID-VTFFPFDQQNCTMKFG----------SWTYDKAKIDLVSMHSRVDQLDFWESGEWVIV- 214

  Fly   399 VENDSQRRYNPK--GMMQKMTGDVAIEFTLQRNRSFYMTVFYLP--LIACQMFLILSFVLRSTRR 459
               |:...||.:  ....::..|:...|.::|...||.....:|  ||:|...|:.........:
Mouse   215 ---DAVGTYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEK 276

  Fly   460 SSLILIALLIAAWGLMYMTR-YASPHYVPPMMTAYKVI-MMTTTYCYILHICIIWLDLYPPRSKA 522
            .:|.:..||.....|:.:|. ..|...|.|::..|.:. |:..|...::.:.::.:....||:..
Mouse   277 VTLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHT 341

  Fly   523 -PGWLVRVINSNVLRCILGLRFSDSTDYCDIQENPWHHMA 561
             |.|:.||....|.|.:...|.|...|.|.......|.||
Mouse   342 MPAWVRRVFLDIVPRLLFMKRPSVVKDNCRRLIESMHKMA 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	44/226 (19%)
Chrna4	NP_056545.3	Neur_chan_LBD	39..245	CDD:280998	43/221 (19%)
		Neur_chan_memb	252..620	CDD:280999	31/130 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	420..459
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	503..529

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900