DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NtR and chrna8

DIOPT Version :9

Sequence 1:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021329572.1	Gene:	chrna8 / 100537531	ZFINID:	ZDB-GENE-090313-161	Length:	516	Species:	Danio rerio

Alignment Length:	364	Identity:	73/364 - (20%)
Similarity:	140/364 - (38%)	Gaps:	52/364 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 SEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMMHWR 268
            ::.||||.|...|  ||..:::..:|                         .:|.|...:.:.|.
Zfish    52 NDSAPIVVELGLT--LLQIIDVDEKN-------------------------QVLITNAWLQLGWT 89

  Fly   269 DSRLVWKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYANGSITLYAQNLQL 333
            |..|.|.|:::..:::...|..:||.|.:.:.|.|.:.......: .::|.|:|:.......: |
Zfish    90 DVYLSWNPDNYPGVQTLRFPSNQIWTPDILLYNSADERFDATFHT-NVLVNASGACQYIPPGI-L 152

  Fly   334 ASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNEHVNTPSG-WSFTQMSVV 397
            .|.|....|.:|.:...||::.|.....|     .:.|.|.:.:..:.::  |:| |.
Zfish   153 KSTCYIDVRWFPFDIQKCDLKFGSWTHNG-----WLLDLQMQAVDISTYI--PNGEWD------- 203

  Fly   398 LVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFLILSFVLRSTRRSSL 462
            ||....:|........::...||....|::|...:|.....:|.:......:|.|:|.:.....:
Zfish   204 LVGVPGKRNELYYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISGLALLVFLLPADSGEKI 268

  Fly   463 IL-IALLIAAWGLMYMTRYASP---HYVPPMMTAYKVIMMTTTYCYILHICIIWLDLYPPR-SKA 522
            .| |.:|::....|.:.....|   ..||.:...:...||......::.:.::....:.|: .|.
Zfish   269 SLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMMIVGLSVVVTVLVLQFHHHDPQGGKM 333

  Fly   523 PGWLVRVINSNVLRCILGLRFSDSTDYCDIQ--ENPWHH 559
            |.| ||||..|.....|.::........:.:  ::|.||
Zfish   334 PRW-VRVILLNWCAWFLRMKKPGEERKANFKYDQSPAHH 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	41/217 (19%)
chrna8	XP_021329572.1	Neur_chan_LBD	12..504	CDD:332142	73/364 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910