Protein Alignment prc and GREP1

DIOPT Version :10

• Sequence 1: NP_524658.2
• Gene: prc / 43930
• FlyBaseID: FBgn0028573
• Length: 1713
• Species: Drosophila melanogaster
• Sequence 2: NP_001383387.1
• Gene: GREP1 / 283875
• HGNCID: 27549
• Length: 519
• Species: Homo sapiens
• Alignment Length: 710
• Identity: 197/710 - (27%)
• Similarity: 250/710 - (35%)
• Gaps: 277/710 - (39%)

  Fly   506 PGVGAQTGAGQPGYGSQPGIGGQTGAGQPGYGTQPGVGAQTGTGQPGYGAQPGVGTQTG------ 564
            ||:|..       ||...|:    |||..| |.:|        .:||:..:.|:|||.|
Human    28 PGLGKV-------YGPHSGL----GAGYDG-GVKP--------QKPGFVVRHGLGTQPGFRTFAG 72

  Fly   565 -AGQPGYGSQPGIGGQTGAGQPGYGTQPGVGAQTGTGQPGYGAQPGVGTQTGAGQPGYGSQPGYG 628
             |.|||||:  |:|   .|..|..|.|.|:|:::|.|.   |..||.||     .|||.:..|.|
Human    73 AAAQPGYGN--GLG---AAAFPVAGAQSGLGSRSGLGA---GTLPGAGT-----PPGYNNGNGPG 124

  Fly   629 TQPGVGAQTGTGQPGYGAQPGVGGQTGAGQPGYGTQPGIGGQTGAGQPGYGSQPGIGGQTGGGQP 693
            ||||..||.|.|                                   ||:|         |||:|
Human   125 TQPGPAAQNGFG-----------------------------------PGFG---------GGGKP 145

  Fly   694 GYGSQIGGQTGAGQPSYGSQPGVGAQNGAGQPGYGTQPVIGGQTGAGQPGYGGQTGVGGSPGFLT 758
                              .:||...|||. :|||         .||.:|         ..|||..
Human   146 ------------------QKPGPTTQNGY-RPGY---------VGAVKP---------QKPGFQY 173

  Fly   759 QPGIGGISGPIGGKLGGGQSEAAKPGYWAQPGIGGPSRYGSQPGIGDQTGTGQSGYGGQPGISGQ 823
            :.|:|                       ||||..|..: ..:|.:     |.|:.:|...|:.|.
Human   174 RIGLG-----------------------AQPGFRGDMK-AQEPVL-----TAQNRFGFGAGLGGN 209

  Fly   824 TGGGQPGYGGQATISGLPGYGTQPGIGALTAVPGGHYGYETQPGIGGQTGTNQPGFGG-----QP 883
            ....:||||.:......||.||||           .||:...||:       |||.|.     .|
Human   210 VKPLKPGYGKRLRAGAFPGAGTQP-----------EYGHGNGPGV-------QPGLGAGMKPQMP 256

  Fly   884 GIGGQTGAGQPGYGFIGQPGIGGQTGTSGRQPGYGTQPGIGGQTAAGQPGYGSQTGVGGQIGAGQ 948
            |:|...|.| ||.|..|.||            |...:|.:........|||      .|.:.|.:
Human   257 GLGAPNGYG-PGRGRAGVPG------------GPERRPWVPHLLPFSSPGY------LGVMKAQK 302

  Fly   949 PGYG-----SQPGIGGQTGAGQPGYGAQPGFGGQPGYGN------------QPGVGGQTGAGQPG 996
            ||.|     .:||:.|.....:.|:|.:.  |..||..|            .|||......|. |
Human   303 PGAGEGMKPQKPGLRGTLKPQKSGHGHEN--GPWPGPCNARVAPMLLPRLPTPGVPSDKEGGW-G 364

  Fly   997 YGSQPGIGGQTG---AGQP--GY--GAQPGFGG-------QLGYGNQPGVGGQTGA-----GQPG 1042
            ..|||....|.|   ..||  ||  ||:|||.|       .|||||     |..||     ..|
Human   365 LKSQPPSAVQNGKLPGHQPPNGYGPGAEPGFNGGLEPQKIGLGYGN-----GVLGARVFPEAHP- 423

  Fly  1043 YGSQPGVGGQTGAGQPGYGVIPGFGGQPGIGG----QTAAGKPGYGGQPGIGGSPVYGTQQGTGG 1103
                          |||:....||..:.|:..    :.||..|...||.|:..:..:.|.|..|
Human   424 --------------QPGFHGANGFRNRDGVEALVYPKAAALAPEGNGQAGVLWNSRWPTLQAWG- 473

  Fly  1104 QSGISGGQPGYGTQPGQTGAGQPGYGSLPGTGGQATAGQPGYGPGSQPGIGGQTVGGHGG 1163
                :|.:|||  |.|...|              ....||| ||..:.|..||...|:||
Human   474 ----AGLKPGY--QAGDEYA--------------EARSQPG-GPDVKRGSNGQLGNGYGG 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prc	NP_524658.2	FhaB	110..1468	CDD:442443	197/710 (28%)
		Glutenin_hmw	148..727	CDD:367362	66/227 (29%)
GREP1	NP_001383387.1	None