Protein Alignment prc and let-2

DIOPT Version :10

• Sequence 1: NP_524658.2
• Gene: prc / 43930
• FlyBaseID: FBgn0028573
• Length: 1713
• Species: Drosophila melanogaster
• Sequence 2: NP_510663.1
• Gene: let-2 / 181708
• WormBaseID: WBGene00002280
• Length: 1759
• Species: Caenorhabditis elegans
• Alignment Length: 1662
• Identity: 519/1662 - (31%)
• Similarity: 633/1662 - (38%)
• Gaps: 452/1662 - (27%)

  Fly    97 NGCSGYQTDYPSSGRILDASGSGGI-GRPDSIISLPGGVGGQTG-AGQAGYGSQLGVGAQAGAGQ 159
            :||:|  ||           |:.|| |||.     |.|:.|..| .|..|...:..:|.....|:
 Worm   122 DGCNG--TD-----------GAPGIPGRPG-----PPGMPGFPGPPGMDGLKGEPAIGYAGAPGE 168

  Fly   160 PGYGDQPGVGTQPG-VGQPGYGSQPGIGGQTG-------------AGQPGYGS-----QPG-IGG 204
            .|.|..||:...|| .|:.||..:.|..|.||             .|.||.||     .|| ||.
 Worm   169 KGDGGMPGMPGLPGPSGRDGYPGEKGDRGDTGNAGPRGPPGEAGSPGNPGIGSIGPKGDPGDIGA 233

  Fly   205 QTGAGQPG-----------YGSQPVVGAQTGTGQPGYGAQ---PGVGTQTG-AGQPGYGSQPGIG 254
            ...||.||           .|.:..:|.:...|:||.|.|   ||.|..:| .|.||...:.|:.
 Worm   234 MGPAGPPGPIASTMSKGTIIGPKGDLGEKGEKGEPGEGGQRGYPGNGGLSGQPGLPGMKGEKGLS 298

  Fly   255 GQTGAR----QPGYVTQPGVGAQTGIGQPGYGAQPGILGQTGAGQPGYGSQPGIGGQTG-AGQPG 314
            |..|.|    :||....||.....|:  .|.|..||:.||  .|:.||..:.|..|.:| .|.||
 Worm   299 GPAGPRGKEGRPGNAGPPGFKGDRGL--DGLGGIPGLPGQ--KGEAGYPGRDGPKGNSGPPGPPG 359

  Fly   315 YGT-------QPGVGAQTGT----GQPGYGAQPG----VGTQTGAGQPGYGSQPGIGGQTG-AGQ 363
            .||       .||:..:.|.    |..||...||    :|...|.|.|||....|:.|..| .|.
 Worm   360 GGTFNDGAPGPPGLPGRPGNPGPPGTDGYPGAPGPAGPIGNTGGPGLPGYPGNEGLPGPKGDKGD 424

  Fly   364 PGYGTQPGVGAQTG-------AGQPGYGAQPGVGAQTGAGQPGYGSQPGIGGQTG---------- 411
            .|....|||...:|       .|:|||...||   |:..|.||...:||:.|..|
 Worm   425 GGIPGAPGVSGPSGIPGLPGPKGEPGYRGTPG---QSIPGLPGKDGKPGLDGAPGRKGENGLPGV 486

  Fly   412 AGQPG--YGSQPGIGGQTGARQP-GYGSQPGVGAQTGA----------------------GQPGY 451
            .|.||  ....||..||.||..| ||..:.||....||                      |.|||
 Worm   487 RGPPGDSLNGLPGAPGQRGAPGPNGYDGRDGVNGLPGAPGTKGDRGGTCSACAPGTKGEKGLPGY 551

  Fly   452 GAQPGVGAQTG-------AGQPGYGSQPGIGGQTGA-GQPGYGSQPGVGAQTG--------AGQP 500
            ..|||.....|       .|..|....||..|:.|: |.||....||:..|.|        .|.|
 Worm   552 SGQPGPQGDRGLPGMPGPVGDAGDDGLPGPAGRPGSPGPPGQDGFPGLPGQKGEPTQLTLRPGPP 616

  Fly   501 GYGAQPGVGAQTG-AGQPGYGSQPGIGGQTG-AGQPGYGTQPGVGAQTG-TGQPGYGAQPGV-GT 561
            ||   ||:..:.| .||||....||..|..| .|.|||..:.|.....| :|:||....||: |.
 Worm   617 GY---PGLKGENGFPGQPGVDGLPGPSGPVGPPGAPGYPGEKGDAGLPGLSGKPGQDGLPGLPGN 678

  Fly   562 --QTGAGQPGYGSQPGIGGQTG-AGQPGYGTQPGVGAQTG------------TGQPGYGAQPGVG 611
              :.|.||||   |||..|..| .|.||....||:....|            .||||....||..
 Worm   679 KGEAGYGQPG---QPGFPGAKGDGGLPGLPGTPGLQGMPGEPAPENQVNPAPPGQPGLPGLPGTK 740

  Fly   612 TQTG-AGQPGYGSQPGYGTQPGVGAQTG-TGQPGYGAQPGVGGQTG-AGQPGYGTQPGIGGQTG- 672
            .:.| .|:||...|||:...||:...:| .|.||....|||.|..| .|.||.   |||.|..|
 Worm   741 GEGGYPGRPGEVGQPGFPGLPGMKGDSGLPGPPGLPGHPGVPGDKGFGGVPGL---PGIPGPKGD 802

  Fly   673 AGQPGYGSQPGIGGQTGGGQPGYGSQIGGQTG----------AGQPSYGSQPGV----------G 717
            .|.||.   ||:.||.  |:||.|  :.||.|          ||.|.....||:          |
 Worm   803 VGNPGL---PGLNGQK--GEPGVG--VPGQPGSPGFPGLKGDAGLPGLPGTPGLEGQRGFPGAPG 860

  Fly   718 AQNGAGQPGYGTQPVIGGQTG----------AGQPGYGGQTGVGGSPGFLTQPGIGGISGPIG-- 770
            .:.|.|.||...||...|:.|          .|.||:.||.|:.|.||...:.|:.|:.|..|
 Worm   861 LKGGDGLPGLSGQPGYPGEKGDAGLPGVPGREGSPGFPGQDGLPGVPGMKGEDGLPGLPGVTGLK 925

  Fly   771 GKLGG-GQSEA----AKPGYWAQ---------------------PGIGGPSRYGSQPGIGDQTGT 809
            |.||. |||.|    ..|||...                     ||:.||.   .:||:....||
 Worm   926 GDLGAPGQSGAPGLPGAPGYPGMKGNAGIPGVPGFKGDGGLPGLPGLNGPK---GEPGVPGMPGT 987

  Fly   810 -GQSGYGGQPGISGQTG-GGQPGYGGQATISGLPGYGTQPGIGALTAVPGGHYGYETQPGIGGQT 872
             |..|.||.||:.|:.| .|.||..|....:||||...:.|       |....|.:...|:.||.
 Worm   988 PGMKGNGGLPGLPGRDGLSGVPGMKGDRGFNGLPGEKGEAG-------PAARDGQKGDAGLPGQP 1045

  Fly   873 GTNQP----GFGGQPGIGGQTGAGQPGYGFIGQP---GIGGQTGTSGRQ-----PGYGTQPGIGG 925
            |...|    |..|.||..|:||.  ||||..|||   |:.|..|.:|||     ||....||..|
 Worm  1046 GLRGPQGPSGLPGVPGFKGETGL--PGYGQPGQPGEKGLPGIPGKAGRQGAPGSPGQDGLPGFPG 1108

  Fly   926 QTAAGQPGYGSQTGVGGQIG-------------AGQPGYGSQPGIGGQTGA----GQPGYGAQPG 973
            .  .|:.||..|.|:.|:.|             :||||....||:.||.|.    |..|.|..||
 Worm  1109 M--KGESGYPGQDGLPGRDGLPGVPGQKGDLGQSGQPGLSGAPGLDGQPGVPGIRGDKGQGGLPG 1171

  Fly   974 FGGQPGYGNQPGVGGQTG-AGQPGYGSQPGIGGQTG-AGQPGYGAQPGFGGQLGYGNQPGVGGQT 1036
            ..|..|....||..|:.| .||||.   ||:||:.| ||.||:   ||..|..||..|.|:.|..
 Worm  1172 IPGDRGMDGYPGQKGENGYPGQPGL---PGLGGEKGFAGTPGF---PGLKGSPGYPGQDGLPGIP 1230

  Fly  1037 G-AGQPGYGSQPGVGGQTG-AGQPGYGVIPGFGGQPGIGGQTAAGKPGYGGQPGIGGSPVYGTQQ 1099
            | .|..|:..|||..|..| :|:.|.|.:||..|||   ||:.||..|..|.||:.|...:....
 Worm  1231 GLKGDSGFPGQPGQEGLPGLSGEKGMGGLPGMPGQP---GQSIAGPVGPPGAPGLQGKDGFPGLP 1292

  Fly  1100 GTGGQSGISG-----------GQPGYGTQPGQTGA-------------------GQPGYGSLPG- 1133
            |..|:||:||           |.||:....|..||                   ||||...|.|
 Worm  1293 GQKGESGLSGLPGAPGLKGESGMPGFPGAKGDLGANGIPGKRGEDGLPGVPGRDGQPGIPGLKGE 1357

  Fly  1134 TGGQATAGQPGY-------GPGSQPGIGGQTVGGHGGYGSQPGIGGAPVYGTQPGGGGQTGVIG- 1190
            .||....||||:       |.|..||..|  ..|..|:   ||..|.|.|..:.|.||..|:.|
 Worm  1358 VGGAGLPGQPGFPGIPGLKGEGGLPGFPG--AKGEAGF---PGTPGVPGYAGEKGDGGLPGLPGR 1417

  Fly  1191 -GQPGQIGDRVGQPG-YGTQT----GQIGAPGRYTDGSQTVPGAVGTGGVVAAGTSGADDAFSQA 1249
             |.||..|. ||.|| .|.|.    |:.|.||        :|||.|..|  ..|..|.|....
 Worm  1418 DGLPGADGP-VGPPGPSGPQNLVEPGEKGLPG--------LPGAPGLRG--EKGMPGLDGPPG-- 1469

  Fly  1250 ESSIGDGQASASAQGKKNGGTAKTQVSGTYSSGGTFSASAMTSDADRAASAQVTGNADGAVSQSQ 1314
                .||......|...:|......:||....||......:        ..|..|.....:..:.
 Worm  1470 ----NDGPPGLPGQRGNDGYPGAPGLSGEKGMGGLPGFPGL--------DGQPGGPGAPGLPGAP 1522

  Fly  1315 GSGGPA---------QSQ-AQVQVAKDGGTKASSQSGGIIQQSQSEVHANDKG------------ 1357
            |:.|||         .|| .:|....:|.||.......:..:...:.|..|.|
 Worm  1523 GAAGPAYRDGFVLVKHSQTTEVPRCPEGQTKLWDGYSLLYIEGNEKSHNQDLGHAGSCLQRFSTM 1587

  Fly  1358 -----------GLADAQSSGPGQTSSQAQIGFRPGQE----------------ANPIA------- 1388
                       ..|.........::|:| |...|..|                ||.||
 Worm  1588 PFLFCDFNNVCNYASRNDKSYWLSTSEA-IPMMPVNEREIEPYISRCAVCEAPANTIAVHSQTIQ 1651

  Fly  1389 ------------------------ANGGGQASSSSGT 1401
                                    |.||||:.||.|:
 Worm  1652 IPNCPAGWSSLWIGYSFAMHTGAGAEGGGQSLSSPGS 1688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prc	NP_524658.2	FhaB	110..1468	CDD:442443	514/1649 (31%)
		Glutenin_hmw	148..727	CDD:367362	240/735 (33%)
let-2	NP_510663.1	gly_rich_SclB	<63..>317	CDD:468478	65/212 (31%)
		gly_rich_SclB	<389..>606	CDD:468478	68/219 (31%)
		gly_rich_SclB	<601..>833	CDD:468478	91/247 (37%)
		gly_rich_SclB	<725..>961	CDD:468478	83/245 (34%)
		gly_rich_SclB	<1003..>1239	CDD:468478	93/252 (37%)
		gly_rich_SclB	<1283..>1504	CDD:468478	72/242 (30%)
		C4	1533..1638	CDD:460201	15/105 (14%)
		C4	1641..1751	CDD:460201	11/48 (23%)