Protein Alignment chm and SAS3

DIOPT Version :9

• Sequence 1: NP_001260192.1
• Gene: chm / 43928
• FlyBaseID: FBgn0028387
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_009501.1
• Gene: SAS3 / 852228
• SGDID: S000000148
• Length: 831
• Species: Saccharomyces cerevisiae
• Alignment Length: 646
• Identity: 192/646 - (29%)
• Similarity: 292/646 - (45%)
• Gaps: 177/646 - (27%)

  Fly   259 SQPVKGGAKGKRSGPTKIQNSDSE-------EERKDKANPMRKLTRSLSMRRTKQQPKQETDSES 316
            ||.|:....|.|: ..::.|||:.       ..|.||.  :.|:.:.|    ..||.|..:::.|
Yeast    29 SQFVRSDTNGHRT-TRRLFNSDASISHRIRGSVRSDKG--LNKIKKGL----ISQQSKLASENSS 86

  Fly   317 DGDL-EDDKIMISKSPAKKPAPSNLNAS---KSKVKREPIGISSGVLSSIKSRPVSPITQTEKKC 377
            ...: .|:|:.....|..:|   |:..|   |.::|.:.|...:......||..::|:..
Yeast    87 QNIVNRDNKMGAVSFPIIEP---NIEVSEELKVRIKYDSIKFFNFERLISKSSVIAPLVN----- 143

  Fly   378 PIEGCDSSGHLSG-----------------NLDKHFLPEACPIYHNMS----------ASECKER 415
              :...|||.|.|                 |::..:..:..|...|.|          ..:.|:.
Yeast   144 --KNITSSGPLIGFQRRVNRLKQTWDLATENMEYPYSSDNTPFRDNDSWQWYVPYGGTIKKMKDF 206

  Fly   416 ANERKLRN-EQRLKMPVNIVTAPGNQNTNLKTLSPEQREFLAKIRESRA------NFKPANNNFL 473
            :.:|.|.. |.::|                         ||..:..|::      |....|:|
Yeast   207 STKRTLPTWEDKIK-------------------------FLTFLENSKSATYINGNVSLCNHN-- 244

  Fly   474 DSKVKLEKDVTDEDREPNLAGLVPDYDLQLFREAQAQASERIEDELKDLPVGKGIKYISMGKYKM 538
                  |.|..:|||:.. .|.||                    .:|:......|:||.:..|::
Yeast   245 ------ETDQENEDRKKR-KGKVP--------------------RIKNKVWFSQIEYIVLRNYEI 282

  Fly   539 KVWYQSPYPDDAARLPKMYICEFCLRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQVDGK 603
            |.||.||:|:...:...::||||||:|..|.....||..||:...|||:||||.|||.||::||:
Yeast   283 KPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGR 347

  Fly   604 RYKQYCQHLCLLAKFFLDHKTLYYDVEPFLFYIMT-LADVDG--------CHIVGYFSKHIPFLQ 659
            ....|||:||||||.|::.||||||||||:|||:| ..|.:.        .|.||||||
Yeast   348 ENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSK------ 406

  Fly   660 EK--NSFYNVSCILTLPPYQRKGYGRLLIDFSYLLTRVEGKIGSPEKPLSDLGLISYRSYWK--- 719
            ||  ::.||:|||||||.|||||||:.|::|||||:|.|.|.|:||||||||||::||::||
Yeast   407 EKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKC 471

  Fly   720 -DVLL---DYLCNRSGN-------TIAIKDVSQETAIYSYDIVSTLQALGMMKYWKGKHIVLKKQ 773
             :|||   |....||.|       .:::.|:::.|.:...|:|..|:.|.::...|.:.:
Yeast   472 AEVLLKLRDSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTDVVFGLEQLQVLYRHKTRSL----- 531

  Fly   774 DVLDEYEERVK--------------RRGTFPKIDDSCLRWQPFI-----------NIQPSS 809
            ..||::...:|              ....:|::....|.|:|.|           |::|::
Yeast   532 SSLDDFNYIIKIDSWNRIENIYKTWSSKNYPRVKYDKLLWEPIILGPSFGINGMMNLEPTA 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chm	NP_001260192.1	zf-C2HC	376..402	CDD:279824	6/42 (14%)
		NAT_SF	526..802	CDD:302625	130/314 (41%)
		MOZ_SAS	584..766	CDD:280097	102/206 (50%)
SAS3	NP_009501.1	SAS2	67..571	CDD:227360	176/582 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I2487
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103737
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R755
SonicParanoid	1	1.000	-	-		X2913
TreeFam	0	0.000	Not matched by this tool.
	6	5.740