DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chm and HAM1

DIOPT Version :9

Sequence 1:	NP_001260192.1	Gene:	chm / 43928	FlyBaseID:	FBgn0028387	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	NP_201266.1	Gene:	HAM1 / 836582	AraportID:	AT5G64610	Length:	445	Species:	Arabidopsis thaliana

Alignment Length:	372	Identity:	164/372 - (44%)
Similarity:	230/372 - (61%)	Gaps:	35/372 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 KIRESRANFKPANNNF------------LDSKVKLEK-DV------TDEDREPNLAGL-VPDYDL 501
            |:.|.|.|:...:|::            ||..:|||: |:      .||..|..:..| :..:..
plant    79 KVIERRKNYNGGHNDYEYYVHYTEFNRRLDEWIKLEQLDLDSVECALDEKVEDKVTSLKMTRHQK 143

  Fly   502 QLFREAQAQASERIE----DELKDLPVGKGIKYISMGKYKMKVWYQSPYPDDAARLPKMYICEFC 562
            :...|...:..|.::    .|.::....|.|..|.:|||:::.||.||:|.:.....|::.||||
plant   144 RKIDETHVEGHEELDAASLREHEEFTKVKNIATIELGKYEIETWYFSPFPPEYNDCVKLFFCEFC 208

  Fly   563 LRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQVDGKRYKQYCQHLCLLAKFFLDHKTLYY 627
            |.:.|.:..::||..||..:|||||||||...|.:::||||:.|.|.|:||.|||.|||||||||
plant   209 LSFMKRKEQLQRHMRKCDLKHPPGDEIYRSSTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYY 273

  Fly   628 DVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQEKNS--FYNVSCILTLPPYQRKGYGRLLIDFSY 690
            ||:.|||||:...|..|||:||||||      ||:|  .||::||||||||||||||:.||.|||
plant   274 DVDLFLFYILCECDDRGCHMVGYFSK------EKHSEEAYNLACILTLPPYQRKGYGKFLIAFSY 332

  Fly   691 LLTRVEGKIGSPEKPLSDLGLISYRSYWKDVLLDYLCNRSGNTIAIKDVSQETAIYSYDIVSTLQ 755
            .|::.|||:|:||:|||||||:|||.||..:|||.|....|| |:||::|..|||.:.||:||||
plant   333 ELSKKEGKVGTPERPLSDLGLVSYRGYWTRILLDILKKHKGN-ISIKELSDMTAIKAEDILSTLQ 396

  Fly   756 ALGMMKYWKGKHIVLKKQDVLDEYEERVKRRGTFPKIDDSCLRWQPF 802
            :|.:::|.||:|::.....|||.:.:...|.|.  .:|.|.:.|.|:
plant   397 SLELIQYRKGQHVICADPKVLDRHLKAAGRGGL--DVDVSKMIWTPY 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chm	NP_001260192.1	zf-C2HC	376..402	CDD:279824
		NAT_SF	526..802	CDD:302625	145/277 (52%)
		MOZ_SAS	584..766	CDD:280097	112/183 (61%)
HAM1	NP_201266.1	PLN00104	1..445	CDD:215056	164/372 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10615
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880