Protein Alignment chm and kat6a

DIOPT Version :10

• Sequence 1: NP_609117.4
• Gene: chm / 43928
• FlyBaseID: FBgn0028387
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001116784.4
• Gene: kat6a / 266966
• ZFINID: ZDB-GENE-021022-3
• Length: 2246
• Species: Danio rerio
• Alignment Length: 831
• Identity: 247/831 - (29%)
• Similarity: 359/831 - (43%)
• Gaps: 206/831 - (24%)

  Fly   138 SVNKPSNPANKPSNPTQRSANNNTNRSLENGEGKRPSLSSSSNSTDDSMKIVKNGR--KVPLKMA 200
            ::.|......:||.  :|..|   ..|:.:|..::..|.....|       ||:|.  ||..|..
Zfish    16 AIKKVKKQKQRPSE--ERICN---AVSMSHGLDRKTVLEHLELS-------VKDGSILKVSNKGL 68

  Fly   201 STVRPKQIRGKL--PPAKKNGGGPVISSDGSSGSESGSNSGDESSSGSESEGSDSSNSYSSQPVK 263
            ::.:.....|:|  |..:..|||....|.|..|...||:    :||.|:..|.|     .::.:|
Zfish    69 NSYKDPDNPGRLSFPKPRAGGGGGGCGSGGGGGGGGGSS----TSSSSKKPGLD-----WNKLIK 124

  Fly   264 GGAKG-KRSGPTKIQNSDSEEERKDKANPMRKLTRSLSM--------------------RRTKQQ 307
            ...:| ...|.:.:::  .|...|.:|:....|:.|.||                    |..||.
Zfish   125 RSLEGLHEPGGSSLKS--IERFLKCQADVAGYLSGSGSMGPGIFHQQLRLALKRACSHGRVVKQG 187

  Fly   308 PKQETDSESDGD-----------------LEDDKIMISKSPAKKPAP------SNLNASKSKVKR 349
            |.....|.|..|                 .|.|:      |..:|.|      .....::.|...
Zfish   188 PLFRLVSRSSHDGTGCVSLDSLPPVRLLPHEQDR------PVAEPIPICSFCLGTKEQNRDKKPE 246

  Fly   350 EPIGI----SSGVLSSIKSRPVSPI-----------TQTEKKCPIEG--------CDSSGHLSGN 391
            |.|..    :||..|.:|..|...:           .:|...|..:|        |||
Zfish   247 ELISCADCGNSGHPSCLKFSPELTVRVKALWWQCIECKTCSSCQDQGKNADNMLFCDS------- 304

  Fly   392 LDKHFLPEAC-PIYHNMS-----ASECKERANERKLRNEQ--RLKMPVNIV-------------- 434
            .|:.|..|.| |....|.     ...|:.|...|||.:::  ::|...|..
Zfish   305 CDRGFHMECCDPPLTRMPKGMWICQICRPREKGRKLLHDKAAQIKRRYNAPLGRPKGRPGRPFKK 369

  Fly   435 ---------------------------------------------------TAPGNQNTNLKTL- 447
                                                               :|.|:...|.||.
Zfish   370 IRGGGRGRRRRGAGGVDQCSQGSSSPHSSSSSSCEGYPGDDRMLFSLREDDSAHGSLRFNKKTKG 434

  Fly   448 -----------SPEQREFLAKI----RESRANFKPANNNFLDSKVKLEKDVT-----DEDREPNL 492
                       ||:.|:..|::    ::.|...|.......|.:....::.:     |||:.|..
Zfish   435 LIDALSKFFTPSPDGRKARAEVVDYSQQYRMRKKGNRKGEHDDRTGDNQECSDSWREDEDKLPGH 499

  Fly   493 AGLVPDYDLQLFREAQAQASERIEDELKDLPVGKGIKYISMGKYKMKVWYQSPYPDDAARLPKMY 557
            ..|. :.|::|||..|..|.:::.......|..:....|..|||:::.||.||||.:.:||||:|
Zfish   500 ENLT-EKDVELFRHIQEIALQKVGVTGPPDPQMRCPSVIEFGKYEIQTWYSSPYPQEYSRLPKLY 563

  Fly   558 ICEFCLRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQVDGKRYKQYCQHLCLLAKFFLDH 622
            :|||||||.||.:.:.:|..||.|.|||.:|||||..:.|::|||.....|||:||||||.||||
Zfish   564 LCEFCLRYMKSRSILYQHMRKCNWFHPPANEIYRKDDVSVFEVDGNVSTIYCQNLCLLAKLFLDH 628

  Fly   623 KTLYYDVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQEKNSFYNVSCILTLPPYQRKGYGRLLID 687
            |||||||||||||::|..|..|||:||||||. ...|:|   ||||||:.||.||||||||.|||
Zfish   629 KTLYYDVEPFLFYVLTQNDNKGCHLVGYFSKE-KHCQQK---YNVSCIMILPQYQRKGYGRFLID 689

  Fly   688 FSYLLTRVEGKIGSPEKPLSDLGLISYRSYWKDVLLDYLCNRSGNTIAIKDVSQETAIYSYDIVS 752
            |||||::.||:.|||||||||||.:||.:||:.|:|:.|.......::|:.:|:.|.|...||.:
Zfish   690 FSYLLSKREGQPGSPEKPLSDLGRLSYMAYWRSVVLECLHEIRDRQLSIRKLSKVTGICPQDITA 754

  Fly   753 TLQALGMMKYWKGKHIVLKKQDVLDEYEERVKRRGTFPKIDDSCLRWQPFI 803
            ||..|.|::......|:::::.::..:..|:|.:....::|..||||.|.|
Zfish   755 TLLNLNMLEQKGDGVIIMRREKLVANHMARLKAKPRLLEVDPDCLRWTPVI 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chm	NP_609117.4	zf-C2HC	376..404	CDD:460240	10/36 (28%)
		PLN00104	<470..802	CDD:215056	154/336 (46%)
kat6a	NP_001116784.4	H15	122..185	CDD:197772	11/64 (17%)
		PHD1_MOZ_MORF	226..283	CDD:277090	10/56 (18%)
		PHD2_KAT6A_6B	285..331	CDD:277002	12/52 (23%)
		PLN00104	446..803	CDD:215056	160/361 (44%)
		PHA03247	<979..1247	CDD:223021