DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chm and samd1b

DIOPT Version :9

Sequence 1:	NP_001260192.1	Gene:	chm / 43928	FlyBaseID:	FBgn0028387	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	XP_005163590.1	Gene:	samd1b / 101884198	ZFINID:	ZDB-GENE-090313-2	Length:	626	Species:	Danio rerio

Alignment Length:	443	Identity:	94/443 - (21%)
Similarity:	146/443 - (32%)	Gaps:	125/443 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TDSSSATPEEK---------PSTNSSAKSQTQTQQQTNSGNAQRRKPVPAASEDKPKPSVAPSSK 86
            |||||.:.|..         .:|..||.|.|. |::..||:.:..:|..:.|.|.|..| :||:.
Zfish    86 TDSSSGSGESVAEQTKHAAFTNTGDSALSLTD-QEEEESGDKEPEEPRVSPSPDPPLQS-SPSTL 148

  Fly    87 KVNNPPKSKLSSDDDEYEDSAPPAKKNSR-----AMGSSTVTAAAAASAARRKPPASVNKPSNPA 146
                           |.||...|....:.     |.|.|..:..|:||..||...|:....|.|.
Zfish   149 ---------------EKEDKILPLHSGNSLVSCGATGCSAGSEKASASKERRSVSAAGGGGSGPR 198

  Fly   147 NKPS-NPTQRSANNNTNRSLENGEGKRPSLSSSSNSTDDSMKIVKNGRKVPLKMASTVRPKQIRG 210
            :..| .....||.:......|..|.|..|..||..         ||....|.|:...|:...:||
Zfish   199 DASSAGEEMLSAGHEGTDEEEEKEQKTCSSVSSPQ---------KNRLSAPSKLKPGVKGSAVRG 254

  Fly   211 KLPPAKKNGGGPVISSDGSSGSESGSNSGDE-----SSSGSESEGSDSSNSYSSQPVK------- 263
                           ||  |..|:.::.||.     .|......||.::..::...:|
Zfish   255 ---------------SD--SPEENSTDLGDRLMDAVRSMSERHRGSAATRGHAPPGLKEILDYLC 302

  Fly   264 -----GGAKGKRSGPTKIQNSDSEEERKDK---------------ANPMRKLTRSLSMRR----- 303
                 .|.|..|:....:...:.|..|..:               |.|..:|.:|....|
Zfish   303 TQKGMPGEKLTRNRVKVVLEREIERGRLRRTRLGHITLPARGMGAAKPSARLLKSALQDRHLAKK 367

  Fly   304 --TKQQPKQETDSESDGDLEDDKIMISKSPAKKPAPSNLNASKSKVKREPIGISSGVLSSIKSRP 366
              .|.:...|.:||.:|         ::.|..:..|..:      ...:|:.:.:|      :.|
Zfish   368 EELKDEDGMEVESEGNG---------TEEPTAEDLPETV------PDEDPVSVKTG------TEP 411

  Fly   367 VSPITQTEK----KCPIEGCDSSGHLSGNLDKHFLPEACPIYHNMSASECKER 415
            .||..:.|.    :.|:..|:.....|.:|.   |...|.|.......|.:|:
Zfish   412 PSPEMEAESDHATRSPMMTCEGESQTSSSLQ---LSNHCSILQQADVGESQEQ 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chm	NP_001260192.1	zf-C2HC	376..402	CDD:279824	5/25 (20%)
		NAT_SF	526..802	CDD:302625
		MOZ_SAS	584..766	CDD:280097
samd1b	XP_005163590.1	SAM_Atherin-like	550..618	CDD:188982
samd1b	XP_005163590.1	SAM	550..617	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900