| Sequence 1: | NP_001137974.1 | Gene: | fal / 43927 | FlyBaseID: | FBgn0028380 | Length: | 368 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056289.2 | Gene: | SAMHD1 / 25939 | HGNCID: | 15925 | Length: | 626 | Species: | Homo sapiens |
| Alignment Length: | 465 | Identity: | 117/465 - (25%) |
|---|---|---|---|
| Similarity: | 182/465 - (39%) | Gaps: | 172/465 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 LIEDEVHGVIELSSHIQEIVEHPLFQRLKHVHQLG----LLPWAIDKKADHKRYDHCLG------ 56
Fly 57 ----AYKSAQDHLRAIERNSHYEPKLPDWCRQAVEIAALLHDIGHGPMSHAW----------ELV 107
Fly 108 THHE------FDHEENAMACVDKIFKDALNQELVSLRDDGGGRGVQLIKALILGSSENLP----- 161
Fly 162 FPMLGH----TYIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEMDFDDVFLQARI-SPDGQ- 220
Fly 221 RIEYRYADYHRVYRLFEARSLLHVKAYQ-------------------------------YPLTCA 254
Fly 255 M----------DVIFVSVVQRIAPEL---------------------------LSIRSKD----- 277
Fly 278 -------PKWL---EL-TDEYVLNVI-------EKDPI---SRYVK-EPHRLVEVPSNDCS---- 316
Fly 317 ---GSDIIRV 323 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fal | NP_001137974.1 | HDc | 48..210 | CDD:238032 | 56/196 (29%) |
| SAMHD1 | NP_056289.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | ||
| SAM_HD | 41..110 | CDD:188907 | |||
| SAM | 42..109 | CDD:197735 | |||
| YdhJ | 115..504 | CDD:224004 | 102/415 (25%) | ||
| HDc | 162..335 | CDD:238032 | 56/196 (29%) | ||
| Substrate binding. /evidence=ECO:0000269|PubMed:24141705 | 309..315 | 5/5 (100%) | |||
| Substrate binding. /evidence=ECO:0000269|PubMed:24141705 | 370..375 | 2/4 (50%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165140818 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1078 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S6883 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D426111at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002596 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89710 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100615 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11373 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2947 |
| SonicParanoid | 1 | 1.000 | - | - | X1701 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.690 | |||||