Protein Alignment jim and ZNF616

DIOPT Version :10

• Sequence 1: NP_001262221.1
• Gene: jim / 43924
• FlyBaseID: FBgn0027339
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: NP_848618.2
• Gene: ZNF616 / 90317
• HGNCID: 28062
• Length: 781
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 133/410 - (32%)
• Similarity: 177/410 - (43%)
• Gaps: 96/410 - (23%)

  Fly   323 HSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTC 387
            |:..:.:||..|||.|.|:..|..|..:||..|||.|:||||.|::.|:||.|..|||.:||:.|
Human   291 HTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFKCNECGKTFKRSSNLTVHQVIHAGKKPYKC 355

  Fly   388 PYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSP------------ 440
            ..|.::||.|:.|..|.|||||||.:.|.||||.|.:::.|..|.|.|....|
Human   356 DVCGKAFRHRSNLVCHRRIHSGEKQYKCNECGKVFSKRSSLAVHRRIHTVEKPCKCNECGKVFSK 420

  Fly   441 ------------------------------HL--------------------IF----KNGPHPT 451
                                          ||                    :|    :...|..
Human   421 RSSLAVHQRIHTGQKTYKCNKCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQR 485

  Fly   452 LWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYP-----SYFKD----GKGQKIL 507
            :...:.|:       |.:..|.....|...:......:|...|.     ..|.|    .:.::|
Human   486 IHTGEKPY-------KCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRI- 542

  Fly   508 PEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHL 572
                 |.|.:|      .:|..|.|.|.|.:.|..|..||...:||.|.||||.:.|.|||..|.
Human   543 -----HTGEKP------YKCKECGKVFSQCSRLTVHRRIHSGEKPYKCNECGKVYSQYSHLVGHR 596

  Fly   573 RIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPF 637
            |:||.|||:.|..|.:.|.|.:.||:|.|||||||||||.|||..|.|:..|..|...|.||||:
Human   597 RVHTGEKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDRPY 661

  Fly   638 CCPMPNCRRRFATENEVTKH 657
            .|  ..|.:.|...:.:|.|
Human   662 KC--NECGKTFKRSSNLTAH 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		COG5048	355..666	CDD:227381	121/378 (32%)
		C2H2 Zn finger	359..379	CDD:275368	10/19 (53%)
		C2H2 Zn finger	387..407	CDD:275368	8/19 (42%)
		C2H2 Zn finger	415..435	CDD:275368	9/19 (47%)
		C2H2 Zn finger	527..547	CDD:275368	7/19 (37%)
		C2H2 Zn finger	555..575	CDD:275368	11/19 (58%)
		C2H2 Zn finger	583..603	CDD:275368	8/19 (42%)
		C2H2 Zn finger	611..631	CDD:275368	8/19 (42%)
		C2H2 Zn finger	639..661	CDD:275368	5/19 (26%)
ZNF616	NP_848618.2	KRAB	7..47	CDD:460171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..129
		SUF4-like	187..>231	CDD:411020
		C2H2 Zn finger	187..208	CDD:411020
		C2H2 Zn finger	187..207	CDD:275368
		C2H2 Zn finger	243..263	CDD:275368
		COG5048	266..707	CDD:227381	133/410 (32%)
		C2H2 Zn finger	271..291	CDD:275368	133/410 (32%)
		C2H2 Zn finger	299..319	CDD:275368	8/19 (42%)
		C2H2 Zn finger	327..347	CDD:275368	10/19 (53%)
		C2H2 Zn finger	355..375	CDD:275368	8/19 (42%)
		C2H2 Zn finger	383..403	CDD:275368	9/19 (47%)
		C2H2 Zn finger	411..431	CDD:275368	0/19 (0%)
		C2H2 Zn finger	439..459	CDD:275368	2/19 (11%)
		C2H2 Zn finger	467..487	CDD:275368	2/19 (11%)
		C2H2 Zn finger	495..515	CDD:275368	2/19 (11%)
		C2H2 Zn finger	523..543	CDD:275368	3/25 (12%)
		C2H2 Zn finger	551..571	CDD:275368	7/19 (37%)
		C2H2 Zn finger	579..599	CDD:275368	11/19 (58%)
		C2H2 Zn finger	607..627	CDD:275368	8/19 (42%)
		C2H2 Zn finger	635..655	CDD:275368	8/19 (42%)
		C2H2 Zn finger	663..683	CDD:275368	5/19 (26%)
		C2H2 Zn finger	691..711	CDD:275368
		zf-H2C2_2	703..726	CDD:463886
		C2H2 Zn finger	719..739	CDD:275368
		zf-H2C2_2	731..756	CDD:463886
		C2H2 Zn finger	747..767	CDD:275368