Protein Alignment jim and GZF1

DIOPT Version :9

• Sequence 1: NP_001262221.1
• Gene: jim / 43924
• FlyBaseID: FBgn0027339
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: NP_001303941.1
• Gene: GZF1 / 64412
• HGNCID: 15808
• Length: 711
• Species: Homo sapiens
• Alignment Length: 770
• Identity: 171/770 - (22%)
• Similarity: 252/770 - (32%)
• Gaps: 273/770 - (35%)

  Fly    51 IGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQ------SPPG 109
            :..|..|...:|..::..:.|....:|:.:.......:.|.|..|:||.....|.      ..||
Human   121 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDSLDYPG 185

  Fly   110 GGQEARDNGSG------------DGRQQQVSPSSSPYPSVQQQQRANG--AG-------DEDPMN 153
               |...||..            |.:::.|.|   |||.:   :||:|  ||       .:....
Human   186 ---ERASNGMSSDLPPKKSKDKLDKKKEVVKP---PYPKI---RRASGRLAGRKVFVEIPKKKYT 241

  Fly   154 HQLANQQNPAPNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGG 218
            .:|..||..|                               :.|.|      ||..|:..:|
Human   242 RRLREQQKTA-------------------------------EGDVG------DYRCPQDQSP--- 266

  Fly   219 MLAPPGFPPLHYLNKGVLPMEQ-SGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAG 282
                         ::....||| |...|...|.|   |.|:       .:.|||......|
Human   267 -------------DRVGTEMEQVSKNEGCQAGAE---LEEL-------SKKAGPEEEEEEE---- 304

  Fly   283 ANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNK-----------------PHSDLR--- 327
                                       ..:..|...|:.                 .||..|
Human   305 ---------------------------EEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGV 342

  Fly   328 ----LFKCLTCGKDFKQKSTLLQHDR-IHTDARPFPCSECGKRFRQQSHLTQH-LRIH-ANEKPF 385
                :::|.|||:.|..:..|..|.| :|:..|.|||..|||:|:::..:.:| |::| ...:..
Human   343 ATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERH 407

  Fly   386 TCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHP 450
            .|..|.:....:..|..|.|.|:|::|:.|.|||..|.|.:.|..|:|.|....|.:
Human   408 RCGQCGKGLSSKTALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFV-------- 464

  Fly   451 TLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIG 515
                                                                             
Human   465 ----------------------------------------------------------------- 464

  Fly   516 VRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKP 580
                       |..|...|.|...|:.|...|...||:.|..|||.|..:.:|..|.||||..||
Human   465 -----------CDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKP 518

  Fly   581 FGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCR 645
            |.|..|.|.|.||..|.||:::||||:||.|.||||.|.|...|.:|.|.|.|:|||.|..  |.
Human   519 FKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNA--CG 581

  Fly   646 RRFATENEVTKHIDNHMNPNT--------TKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQV 702
            |.|..::.:.:|...| :.||        .....:....|:.:|..::               .|
Human   582 RTFTDKSTLRRHTSIH-DKNTPWKSFLVIVDGSPKNDDGHKTEQPDEE---------------YV 630

  Fly   703 ANHLMNDAKSLAAQQFLNNNNPSAVDNKANILPVRSIASNAAAAAVVQQSVVKNE 757
            ::.|.:...|.|.....  :|.:||.   :.:|.....|:|..|.....|||..:
Human   631 SSKLSDKLLSFAENGHF--HNLAAVQ---DTVPTMQENSSADTACKADDSVVSQD 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	8/20 (40%)
		COG5048	355..666	CDD:227381	89/312 (29%)
		zf-C2H2	357..379	CDD:278523	9/22 (41%)
		C2H2 Zn finger	359..379	CDD:275368	7/20 (35%)
		zf-H2C2_2	371..396	CDD:290200	5/26 (19%)
		C2H2 Zn finger	387..407	CDD:275368	5/19 (26%)
		zf-H2C2_2	400..424	CDD:290200	11/23 (48%)
		C2H2 Zn finger	415..435	CDD:275368	9/19 (47%)
		C2H2 Zn finger	527..547	CDD:275368	6/19 (32%)
		zf-C2H2	553..575	CDD:278523	8/21 (38%)
		C2H2 Zn finger	555..575	CDD:275368	8/19 (42%)
		C2H2 Zn finger	583..603	CDD:275368	9/19 (47%)
		zf-H2C2_2	596..620	CDD:290200	15/23 (65%)
		C2H2 Zn finger	611..631	CDD:275368	10/19 (53%)
		zf-H2C2_2	624..650	CDD:290200	12/25 (48%)
		C2H2 Zn finger	639..661	CDD:275368	5/21 (24%)
GZF1	NP_001303941.1	BTB	21..133	CDD:306997	2/11 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..220		17/75 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	243..312		24/162 (15%)
		C2H2 Zn finger	319..339	CDD:275368	2/19 (11%)
		C2H2 Zn finger	350..371	CDD:275368	8/20 (40%)
		COG5048	<405..593	CDD:227381	76/273 (28%)
		C2H2 Zn finger	409..429	CDD:275368	5/19 (26%)
		C2H2 Zn finger	437..457	CDD:275368	9/19 (47%)
		C2H2 Zn finger	465..485	CDD:275368	6/19 (32%)
		C2H2 Zn finger	493..513	CDD:275368	8/19 (42%)
		C2H2 Zn finger	521..541	CDD:275368	9/19 (47%)
		C2H2 Zn finger	549..569	CDD:275368	10/19 (53%)
		C2H2 Zn finger	577..597	CDD:275368	5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100