DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jim and znf1102

DIOPT Version :9

Sequence 1:	NP_001262221.1	Gene:	jim / 43924	FlyBaseID:	FBgn0027339	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	XP_017211012.2	Gene:	znf1102 / 565794	ZFINID:	ZDB-GENE-071004-71	Length:	1352	Species:	Danio rerio

Alignment Length:	376	Identity:	144/376 - (38%)
Similarity:	192/376 - (51%)	Gaps:	42/376 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 GNGPGRPHKNKPHSDL----RLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSH 371
            |...||.:..|.|..:    :.|.|..|||.|.|||.|..|..|||..:||.|:.|||.|...||
Zfish    72 GKSFGRKYNLKIHMKIHTGEKPFTCTQCGKSFSQKSNLNLHIMIHTGEKPFTCTHCGKSFNHLSH 136

  Fly   372 LTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQ 436
            |.||:|||..||||||..|.:||.|.:.||.|::||:|||||.|.:|||.|||.:.|..|:..|.
Zfish   137 LNQHMRIHTGEKPFTCTQCGKSFSQSSHLNCHMKIHTGEKPFTCTQCGKSFRQSSSLTLHMMIHT 201

  Fly   437 DVSPHLIFKNG----------PHPTLWPSDVPFP----GEDNDTKGDIAGTGGGY-HDEDSQGTP 486
            ...|....:.|          .|..:...:.|||    |:..::..::      | |..:..|
Zfish   202 REKPFTCSQCGKSYSQSSYLNDHMMIHTGEKPFPCTQCGKSFNSSSNL------YKHMRNHTG-- 258

  Fly   487 DGSGGMHYP-SYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIES 550
                  ..| |..:.||....|..:.:|:.:.....|.  .||.|.|.|.|.:.|.||..||...
Zfish   259 ------EKPFSCTQCGKSFNHLSNLHRHMRIHTGEKPF--TCPQCGKSFSQSSHLNQHMMIHTGE 315

  Fly   551 RPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCG 615
            :|:.||||||.|.::.:|..|:||||.||||.|..|.:.|.|.:.|..|:.|||||||:||.|||
Zfish   316 KPFICPECGKSFGRKHNLKIHMRIHTGEKPFKCTQCGKSFNQSSNLYNHMMIHTGEKPFKCTQCG 380

  Fly   616 KDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNT 666
            |.|.:.:.|.||.|.|.|::|:.|  ..|.:.|    ..:.|:..||..:|
Zfish   381 KSFNRSSDLHQHMRIHTGEKPYTC--TQCGKSF----YCSSHLHQHMRIHT 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	10/19 (53%)
		COG5048	355..666	CDD:227381	124/326 (38%)
		zf-C2H2	357..379	CDD:278523	12/21 (57%)
		C2H2 Zn finger	359..379	CDD:275368	11/19 (58%)
		zf-H2C2_2	371..396	CDD:290200	16/24 (67%)
		C2H2 Zn finger	387..407	CDD:275368	8/19 (42%)
		zf-H2C2_2	400..424	CDD:290200	15/23 (65%)
		C2H2 Zn finger	415..435	CDD:275368	9/19 (47%)
		C2H2 Zn finger	527..547	CDD:275368	9/19 (47%)
		zf-C2H2	553..575	CDD:278523	10/21 (48%)
		C2H2 Zn finger	555..575	CDD:275368	10/19 (53%)
		C2H2 Zn finger	583..603	CDD:275368	6/19 (32%)
		zf-H2C2_2	596..620	CDD:290200	16/23 (70%)
		C2H2 Zn finger	611..631	CDD:275368	10/19 (53%)
		zf-H2C2_2	624..650	CDD:290200	10/25 (40%)
		C2H2 Zn finger	639..661	CDD:275368	4/21 (19%)
znf1102	XP_017211012.2	C2H2 Zn finger	68..88	CDD:275368	5/15 (33%)
		zf-H2C2_2	80..105	CDD:316026	8/24 (33%)
		C2H2 Zn finger	96..116	CDD:275368	10/19 (53%)
		C2H2 Zn finger	124..144	CDD:275368	11/19 (58%)
		zf-H2C2_2	136..161	CDD:316026	16/24 (67%)
		C2H2 Zn finger	152..172	CDD:275368	8/19 (42%)
		C2H2 Zn finger	180..200	CDD:275368	9/19 (47%)
		C2H2 Zn finger	208..228	CDD:275368	2/19 (11%)
		zf-H2C2_2	220..245	CDD:316026	5/24 (21%)
		C2H2 Zn finger	236..256	CDD:275368	3/25 (12%)
		COG5048	260..723	CDD:227381	70/174 (40%)
		C2H2 Zn finger	264..284	CDD:275368	4/19 (21%)
		C2H2 Zn finger	292..312	CDD:275368	9/19 (47%)
		C2H2 Zn finger	320..340	CDD:275368	10/19 (53%)
		C2H2 Zn finger	348..368	CDD:275368	6/19 (32%)
		C2H2 Zn finger	376..396	CDD:275368	10/19 (53%)
		C2H2 Zn finger	404..424	CDD:275368	6/25 (24%)
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	545..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
		C2H2 Zn finger	684..704	CDD:275368
		C2H2 Zn finger	712..732	CDD:275368
		zf-H2C2_2	724..749	CDD:316026
		C2H2 Zn finger	740..760	CDD:275368
		zf-H2C2_2	752..777	CDD:316026
		C2H2 Zn finger	768..788	CDD:275368
		zf-H2C2_2	780..804	CDD:316026
		C2H2 Zn finger	796..816	CDD:275368
		COG5048	820..1201	CDD:227381
		C2H2 Zn finger	824..844	CDD:275368
		C2H2 Zn finger	852..872	CDD:275368
		C2H2 Zn finger	880..900	CDD:275368
		C2H2 Zn finger	932..952	CDD:275368
		C2H2 Zn finger	960..980	CDD:275368
		C2H2 Zn finger	988..1008	CDD:275368
		C2H2 Zn finger	1016..1036	CDD:275368
		C2H2 Zn finger	1044..1064	CDD:275368
		C2H2 Zn finger	1072..1092	CDD:275368
		C2H2 Zn finger	1100..1120	CDD:275368
		C2H2 Zn finger	1128..1148	CDD:275368
		C2H2 Zn finger	1156..1176	CDD:275368
		C2H2 Zn finger	1184..1204	CDD:275368
		C2H2 Zn finger	1212..1232	CDD:275368
		C2H2 Zn finger	1240..1260	CDD:275368
		zf-H2C2_2	1252..1277	CDD:316026
		C2H2 Zn finger	1268..1288	CDD:275368
		zf-H2C2_2	1280..1305	CDD:316026
		C2H2 Zn finger	1296..1316	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910