DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jim and ZNF429

DIOPT Version :9

Sequence 1:	NP_001262221.1	Gene:	jim / 43924	FlyBaseID:	FBgn0027339	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	XP_016882237.1	Gene:	ZNF429 / 353088	HGNCID:	20817	Length:	689	Species:	Homo sapiens

Alignment Length:	354	Identity:	130/354 - (36%)
Similarity:	173/354 - (48%)	Gaps:	59/354 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 HKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANE 382
            || :.||..:.:||..|||.|...||..:|..|||:.:|:.|.||||.|.:.|.||.|.|||..|
Human   290 HK-RIHSGEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGE 353

  Fly   383 KPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNG 447
            ||:.|..|.::|...:.|.:|..||:||||:.|.||||.|.|.:.|.:|.:.|....|:...|.|
Human   354 KPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCG 418

  Fly   448 PHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQ 512
            ...|.                            .|..|.|                :||
Human   419 RVFTC----------------------------SSTLTQD----------------KKI------ 433

  Fly   513 HIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTN 577
            |.|.:|.|      |..|.|.|...:||.:|..||.|.:||.|.||||.|.:.||||.|.||||.
Human   434 HTGEKPYN------CEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTG 492

  Fly   578 EKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMP 642
            |||:.|..|.:.|:|.:.||.|.:||:|||||||.:|||.|...:.|.||.:.|.|::|:.|  .
Human   493 EKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKIHTGEKPYKC--E 555

  Fly   643 NCRRRFATENEVTKHIDNHMNPNTTKVRR 671
            .|.:.|...:.:|:|...|......|.::
Human   556 ECGKAFNRSSRLTQHKKIHTGEKPYKCKQ 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		COG5048	355..666	CDD:227381	113/310 (36%)
		zf-C2H2	357..379	CDD:278523	11/21 (52%)
		C2H2 Zn finger	359..379	CDD:275368	11/19 (58%)
		zf-H2C2_2	371..396	CDD:290200	12/24 (50%)
		C2H2 Zn finger	387..407	CDD:275368	5/19 (26%)
		zf-H2C2_2	400..424	CDD:290200	14/23 (61%)
		C2H2 Zn finger	415..435	CDD:275368	9/19 (47%)
		C2H2 Zn finger	527..547	CDD:275368	7/19 (37%)
		zf-C2H2	553..575	CDD:278523	13/21 (62%)
		C2H2 Zn finger	555..575	CDD:275368	12/19 (63%)
		C2H2 Zn finger	583..603	CDD:275368	7/19 (37%)
		zf-H2C2_2	596..620	CDD:290200	16/23 (70%)
		C2H2 Zn finger	611..631	CDD:275368	8/19 (42%)
		zf-H2C2_2	624..650	CDD:290200	9/25 (36%)
		C2H2 Zn finger	639..661	CDD:275368	5/21 (24%)
ZNF429	XP_016882237.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000